Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SARS1 | P49591 | 3/20 | 0.43 |
| ▸ | ADK | P55263 | 6/20 | 0.38 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.38 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.37 |
| ▸ | MARS1 | P56192 | 2/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | QARS1 | P47897 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7104843 | 0.88 | DOT1L (0.40) | SARS1ADKLARS1 | |
| SCHEMBL6510822 | 0.79 | IARS1 (0.51) | HSPA8 | |
| SCHEMBL7107353 | 0.78 | ADK (0.41) | ADK | |
| SCHEMBL4299948 | 0.71 | ADK (0.43) | ADKHSPA8FBP1 | |
| SCHEMBL10005056 | 0.70 | HSPA8 (0.41) | ADKHSPA8FBP1 | |
| SCHEMBL11043640 | 0.69 | HSPA8 (0.39) | ADKHSPA8FBP1 | |
| SCHEMBL11165275 | 0.68 | HSPA8 (0.38) | ADKHSPA8FBP1 | |
| SCHEMBL11310700 | 0.67 | HSPA8 (0.36) | ADKHSPA8FBP1 | |
| SCHEMBL11041141 | 0.67 | HSPA8 (0.37) | ADKHSPA8FBP1 | |
| SCHEMBL11042514 | 0.66 | HSPA8 (0.37) | ADKHSPA8FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991412-B1 | AMINOACYL SULFAMIDES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | CUBIST PHARM INC (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5824657-A | ANTICARCINOGENIC AGENTS, SKIN DISORDERS AND PSORIASIS | CUBIST PHARMACEUTICALS, INC. (US) | 1998-10-20 | — | — | US | disclosed |