Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IARS1 | P41252 | 7/20 | 0.51 |
| ▸ | TARS1 | P26639 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110520 | 0.79 | SARS1 (0.43) | HSPA8 | |
| SCHEMBL846742 | 0.74 | HSPA8 (0.46) | HIF1AHSPA8 | |
| SCHEMBL7104843 | 0.74 | DOT1L (0.40) | — | |
| SCHEMBL177666 | 0.73 | HSPA8 (0.44) | HIF1AHSPA8 | |
| SCHEMBL1976100 | 0.73 | HSPA8 (0.46) | HIF1AHSPA8 | |
| SCHEMBL830796 | 0.72 | MAPK1 (0.50) | HIF1AHSPA8 | |
| SCHEMBL830795 | 0.72 | MAPK1 (0.50) | HIF1AHSPA8 | |
| SCHEMBL2197504 | 0.72 | CDK1 (0.48) | HIF1AHSPA8 | |
| SCHEMBL724943 | 0.70 | MAPK1 (0.50) | HIF1AHSPA8 | |
| SCHEMBL1936249 | 0.70 | ADK (0.50) | HIF1AHSPA8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050181464-A1 | Novel purified polypeptides from bacteria | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2005-08-18 | — | — | US | disclosed |
| WO-2003102190-A2 | BACTERIAL POLYPEPTIDES INVOLVED IN VIABILITY | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2003-12-11 | — | — | WO | disclosed |