Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 8/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.37 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.34 |
| ▸ | SARS1 | P49591 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107353 | 0.89 | ADK (0.41) | ADK | |
| SCHEMBL7110520 | 0.88 | SARS1 (0.43) | ADKLARS1SARS1 | |
| SCHEMBL6510822 | 0.74 | IARS1 (0.51) | — | |
| SCHEMBL2291125 | 0.67 | ADK (0.36) | ADKAKT1 | |
| SCHEMBL10005056 | 0.66 | HSPA8 (0.41) | ADK | |
| SCHEMBL31533322 | 0.66 | DOT1L (0.71) | DOT1LLARS1SARS1 | |
| SCHEMBL7665106 | 0.66 | HSPA8 (0.40) | NPEPPS | |
| SCHEMBL11165275 | 0.65 | HSPA8 (0.38) | ADK | |
| Phesa SCHEMBL3499221 | 0.64 | SARS1 (0.80) | LARS1SARS1 | |
| Phesa SCHEMBL3499217 | 0.64 | SARS1 (0.80) | LARS1SARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991412-B1 | AMINOACYL SULFAMIDES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | CUBIST PHARM INC (US) | 2003-03-12 | — | — | EP | claimed |
| US-5824657-A | ANTICARCINOGENIC AGENTS, SKIN DISORDERS AND PSORIASIS | CUBIST PHARMACEUTICALS, INC. (US) | 1998-10-20 | — | — | US | claimed |
| EP-0991412-B1 | AMINOACYL SULFAMIDES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | CUBIST PHARM INC (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-0991412-B1 | AMINOACYL SULFAMIDES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | CUBIST PHARM INC (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-0991412-A4 | AMINOACYL SULFAMIDES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | CUBIST PHARM INC (US) | 2000-06-21 | — | — | EP | disclosed |
| EP-0991412-A1 | AMINOACYL SULFAMIDES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | Cubist Pharmaceuticals, Inc. (US) | 2000-04-12 | — | — | EP | disclosed |
| US-5824657-A | ANTICARCINOGENIC AGENTS, SKIN DISORDERS AND PSORIASIS | CUBIST PHARMACEUTICALS, INC. (US) | 1998-10-20 | — | — | US | disclosed |
| US-5824657-A | ANTICARCINOGENIC AGENTS, SKIN DISORDERS AND PSORIASIS | CUBIST PHARMACEUTICALS, INC. (US) | 1998-10-20 | — | — | US | disclosed |
| WO-1998041215-A1 | AMINOACYL SULFAMIDES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | CUBIST PHARMACEUTICALS, INC. (US) | 1998-09-24 | — | — | WO | disclosed |