SCHEMBL711068

SCHEMBL711068

Nc1cccc(NC(=O)Nc2ccccc2)c1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDX3X O00571 2/20 0.89
HDAC3 O15379 1/20 0.66
HDAC4 P56524 1/20 0.66
HDAC1 Q13547 1/20 0.66
HDAC7 Q8WUI4 1/20 0.66
HDAC2 Q92769 1/20 0.66
HDAC10 Q969S8 1/20 0.66
HDAC11 Q96DB2 1/20 0.66
HDAC8 Q9BY41 1/20 0.66
HDAC6 Q9UBN7 1/20 0.66
HDAC9 Q9UKV0 1/20 0.66
HDAC5 Q9UQL6 1/20 0.66
SMN1; SMN2 Q16637 3/20 0.65
TP53 P04637 2/20 0.65
EPHX1 P07099 1/20 0.65
TSHR P16473 1/20 0.65
EPHX2 P34913 1/20 0.65
CDK9 P50750 1/20 0.65
CLK4 Q9HAZ1 1/20 0.65
ALDH1A1 P00352 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30314470 0.94 DDX3X (1.00) DDX3XHDAC3HDAC4HDAC1HDAC7
SCHEMBL1657499 0.94 DDX3X (1.00) DDX3XHDAC3HDAC4HDAC1HDAC7
SCHEMBL21305504 0.87 DDX3X (0.68) DDX3XHDAC3HDAC4HDAC1HDAC7
SCHEMBL14350754 0.86 DDX3X (0.77) DDX3XSMN1; SMN2TP53ALDH1A1MAPT
SCHEMBL17193484 0.86 TP53 (0.81) DDX3XSMN1; SMN2TP53EPHX1TSHR
SCHEMBL9233836 0.85 DDX3X (0.81) DDX3XHDAC3HDAC4HDAC1HDAC7
SCHEMBL1025424 0.84 DDX3X (0.74) DDX3XHDAC3HDAC4HDAC1HDAC7
SCHEMBL27877501 0.84 DDX3X (0.79) DDX3XSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL709095 0.84 DDX3X (0.79) DDX3XSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL30987791 0.83 ALDH1A1 (0.72) DDX3XSMN1; SMN2TP53TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2923851-B1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND NIPPON SODA CO (JP) 2019-05-01 EP disclosed
CN-104797429-B Recording material using non-phenolic compound, recording sheet, and method for using non-phenolic compound for color developer 日本曹达株式会社 2017-04-19 CN disclosed
US-9518011-B2 Recording material produced using non-phenol compound NIPPON SODA CO., LTD. (JP) 2016-12-13 US disclosed
US-9518011-B2 Recording material produced using non-phenol compound NIPPON SODA CO., LTD. (JP) 2016-12-13 US disclosed
US-20150284321-A1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND NIPPON SODA CO., LTD. (JP) 2015-10-08 US disclosed
US-20150284321-A1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND NIPPON SODA CO., LTD. (JP) 2015-10-08 US disclosed
EP-2923851-A1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND Nippon Soda Co., Ltd. (JP) 2015-09-30 EP disclosed
CN-104797429-A Recording material using non-phenolic compound NIPPON SODA CO 2015-07-22 CN disclosed
WO-2014080615-A1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND 日本曹達株式会社 (JP) 2014-05-30 WO disclosed
CN-103709097-A 1,3-substituted carbamide or thiourea compound, preparation method thereof, pharmaceutical composition and application SHANGHAI INST MATERIA MEDICA 2014-04-09 CN disclosed
US-20090023743-A1 INHIBITORS OF PROTEIN KINASES ABBOTT LABORATORIES (IL) 2009-01-22 US disclosed
WO-2008141145-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITORS OF PROTEIN KINASES ABBOTT LABORATORIES (US) 2008-11-20 WO disclosed
WO-2008141140-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITORS OF PROTEIN KINASES ABBOTT LABORATORIES (US) 2008-11-20 WO disclosed
CN-101087788-A Quinoline derivative, its use, production and pharmaceutical agents containing the latter BAYER SCHERING PHARMA AG (DE) 2007-12-12 CN disclosed
US-20060167035-A1 Quinoline derivative, its use, production and pharmaceutical agents containing the latter BAYER INTELLECTUAL PROPERTY GMBH (DE) 2006-07-27 US disclosed
EP-0713483-B1 AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES ASTRAZENECA AB (SE) 2003-01-15 EP disclosed
US-5807885-A Amidine derivatives with nitric oxide synthetase activities ASTRA AKTIEBOLAG (SE) 1998-09-15 US disclosed
WO-1995005363-A1 AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES ASTRA AKTIEBOLAG (SE) 1995-02-23 WO disclosed
EP-0162386-A2 Reactive azo dyes BASF Aktiengesellschaft (DE) 1985-11-27 EP disclosed
US-4420308-A Process for the production of reserve effects on polyester textiles and polyester/cellulose mixed fibre textiles: discharge printing with disperse azo dye with alkyl or alkoxy carbonyl, cyand and hydroxy phenyl group CASSELLA AKTIENGESELLSCHAFT (DE) 1983-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090023743-A1 INHIBITORS OF PROTEIN KINASES AURKC, AURKB, PLK1 DDX3X 1508/4885HDAC3 1233/4885HDAC4 1702/4885
US-20060167035-A1 Quinoline derivative, its use, production and pharmaceutical agents containing the latter NQO2, RECQL, XDH DDX3X 719/4885HDAC3 1156/4885HDAC4 2369/4885
US-20150284321-A1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND CYP19A1, ALPG, ALPP DDX3X 630/4885HDAC3 1792/4885HDAC4 1410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.