Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | PKM | P14618 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | CCR8 | P51685 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109833 | 0.84 | CLK4 (0.35) | SMN1; SMN2NPC1RAB9ATP53KDM4E | |
| SCHEMBL7454492 | 0.84 | ADRA1A (0.36) | KDM4EGAAHSD17B10ALDH1A1TYK2 | |
| SCHEMBL7111088 | 0.76 | ADRA1A (0.35) | HCRTR1HCRTR2CYP1A2ADRA1DADRA1A | |
| SCHEMBL20172587 | 0.70 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9ATP53KDM4E | |
| SCHEMBL7446349 | 0.67 | KDM4E (0.42) | SMN1; SMN2NPC1RAB9ATP53KDM4E | |
| SCHEMBL29496935 | 0.67 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9ATP53KDM4E | |
| SCHEMBL2039527 | 0.67 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9ATP53KDM4E | |
| SCHEMBL7111089 | 0.67 | SMN1; SMN2 (0.42) | SMN1; SMN2NPC1RAB9ATP53KDM4E | |
| SCHEMBL7107797 | 0.67 | SMN1; SMN2 (0.36) | SMN1; SMN2NPC1RAB9ATP53KDM4E | |
| SCHEMBL26260016 | 0.66 | KDM4E (0.58) | SMN1; SMN2NPC1RAB9ATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030008901-A1 | Hydroxy pipecolate hydroxamic acid derivatives | MCCLURE KIM F (US) | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008901-A1 | Hydroxy pipecolate hydroxamic acid derivatives | MMP1, MMP10, MMP3 | SMN1; SMN2 3318/4885NPC1 3537/4885RAB9A 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.