Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448332 | 0.89 | MTNR1A (0.32) | TSHRMTNR1AMTNR1B | |
| SCHEMBL8447931 | 0.84 | MTNR1A (0.33) | TSHRMTNR1AMTNR1BTGFBR1 | |
| SCHEMBL8447280 | 0.81 | MTNR1A (0.33) | TSHRMTNR1AMTNR1BCHRM1CHRM2 | |
| SCHEMBL16805864 | 0.80 | TSHR (0.38) | TSHRALDH1A1MTNR1AMTNR1BTHRB | |
| SCHEMBL8451742 | 0.79 | MTNR1A (0.33) | TSHRMTNR1AMTNR1BTGFBR1 | |
| SCHEMBL339839 | 0.79 | TSHR (0.35) | TSHRMTNR1AMTNR1BTHRBTGFBR1 | |
| SCHEMBL24513273 | 0.76 | TGFBR1 (0.37) | TSHRALDH1A1MTNR1AMTNR1BTHRB | |
| SCHEMBL20901035 | 0.74 | ALDH1A1 (0.38) | TSHRALDH1A1MTNR1AMTNR1BTGFBR1 | |
| SCHEMBL11419538 | 0.74 | FAAH (0.36) | TSHRMTNR1AMTNR1BTGFBR1RAB9A | |
| SCHEMBL7110870 | 0.74 | TSHR (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627942-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1994-12-14 | — | — | EP | disclosed |
| WO-1993017718-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING A/S (NO) | 1993-09-16 | — | — | WO | disclosed |