Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110437 | 0.81 | ALDH1A1 (0.58) | HSD11B1HSD17B10ACHECA1CA2 | |
| SCHEMBL8961556 | 0.81 | ALDH1A1 (0.58) | HSD11B1HSD17B10ACHECA1CA2 | |
| SCHEMBL836917 | 0.79 | ESR1 (0.53) | HSD11B1HSD17B10ACHECA1CA2 | |
| SCHEMBL15279922 | 0.78 | HSPB1 (0.59) | HSD11B1HSD17B10ACHEALDH1A1KDM4E | |
| SCHEMBL28139668 | 0.77 | ALDH1A1 (0.55) | HSD17B10ACHECA1CA2CA5A | |
| SCHEMBL16031 | 0.77 | — | — | |
| SCHEMBL8198662 | 0.76 | APP (0.57) | HSD17B10ALDH1A1POLBMAPK1LMNA | |
| SCHEMBL1023276 | 0.76 | HSD11B1 (0.60) | HSD11B1HSD17B10ACHECA1CA2 | |
| SCHEMBL397351 | 0.76 | HSD17B10 (0.56) | HSD11B1HSD17B10ACHECA1CA2 | |
| SCHEMBL677959 | 0.76 | HSD17B10 (0.56) | HSD11B1HSD17B10ACHECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109819-B1 | FERROCENE-BASED DIPHOSPHONITES FOR ASYMMETRICAL CATALYSIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2003-04-16 | — | — | EP | disclosed |