Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28096322 | 1.00 | ALDH1A1 (0.68) | ALDH1A1TSHRTRPA1TAAR1CES2 | |
| SCHEMBL1374017 | 1.00 | ALDH1A1 (0.68) | ALDH1A1TSHRTRPA1TAAR1CES2 | |
| Biphenyl SCHEMBL27732862 | 1.00 | ALDH1A1 (0.68) | ALDH1A1TSHRTRPA1TAAR1CES2 | |
| Hydrochloric Acid SCHEMBL28118078 | 0.97 | ALDH1A1 (0.65) | ALDH1A1TSHRTRPA1TAAR1CES2 | |
| SCHEMBL5498364 | 0.95 | ALDH1A1 (0.62) | ALDH1A1TSHRTRPA1TAAR1CES2 | |
| Biphenyl SCHEMBL7524026 | 0.92 | TSHR (0.82) | ALDH1A1TSHRTRPA1TAAR1CES2 | |
| SCHEMBL679626 | 0.88 | TSHR (0.56) | ALDH1A1TSHRTRPA1TAAR1CES2 | |
| SCHEMBL9609757 | 0.88 | TSHR (0.56) | ALDH1A1TSHRTRPA1TAAR1CES2 | |
| SCHEMBL9023806 | 0.87 | ALDH1A1 (0.59) | ALDH1A1TSHRTRPA1TAAR1CES2 | |
| Acetic Acid SCHEMBL28491683 | 0.87 | CES2 (0.57) | ALDH1A1TSHRTRPA1TAAR1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1441 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | claimed |
| US-12509426-B1 | Carbon-14 radioisotope-labeled flonicamid and synthesis method thereof | Zhejiang Isotope Labelled Compounds Co., Ltd (CN) | 2025-12-30 | — | — | US | claimed |
| CN-120040988-A | Unconventional dye for regulating and controlling photosensitive Type I/II process switching of tumor microenvironment and synthetic method and application thereof | 大连理工大学 | 2025-05-27 | — | — | CN | claimed |
| CN-115850002-B | Method for hydrodehalogenating halogenated alkane | 中国科学院兰州化学物理研究所 | 2025-05-23 | — | — | CN | claimed |
| CN-115959962-B | Visible light-promoted halogenated alkane hydrodehalogenation method | 中国科学院兰州化学物理研究所 | 2025-05-23 | — | — | CN | claimed |
| US-12304917-B1 | Pleuromutilin derivative containing a thiazolo[5,4-c]pyridine side chain, and a preparation method and application thereof | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2025-05-20 | — | — | US | claimed |
| US-12275734-B1 | Pleuromutilin onium salt derivative containing a 3H-imidazo[4,5-c]pyridine side chain, and a preparation method and application thereof | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2025-04-15 | — | — | US | claimed |
| CN-119285540-B | Radioisotope carbon-14 labeled flonicamid and synthesis method thereof | 浙江爱索拓标记医药科技有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-119409638-A | Preparation method and application of imidazole-based ionic liquid corrosion inhibitor | 四川轻化工大学 | 2025-02-11 | — | — | CN | claimed |
| CN-119285540-A | Radioisotope carbon-14 labeled flonicamid and synthesis method thereof | 浙江爱索拓标记医药科技有限公司 | 2025-01-10 | — | — | CN | claimed |
| WO-2005122699-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF N-SUBSTITUTED HETERO CYCLIC DERIVATIVES | MATRIX LABORATORIES LTD (IN) | 2005-12-29 | — | — | WO | claimed |
| EP-1210322-B1 | METHOD FOR CARRYING OUT THE SIDE CHAIN BROMINATION OF 4-METHYL BIPHENYL DERIVATIVES SUBSTITUTED AT THE 2'-POSITION | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-02-09 | — | — | EP | claimed |
| EP-1032557-B1 | METHOD FOR PREPARING BROMOMETHYL-BIPHENYL DERIVATIVES | SANOFI SYNTHELABO (FR) | 2003-09-10 | — | — | EP | claimed |
| US-20020095042-A1 | Process for brominating the side chain of 4-methylbiphenyl derivatives substituted in the 2' position | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-07-18 | — | — | US | claimed |
| US-6214999-B1 | A BROMINATING AGENT IS REACTED IN A 2 PHASE MEDIUM, UNDER EFFECT PHOTO-IRRADIATION WITH BIPHENYL DERIVATIVE | SANOFI-SYNTHELABO (FR) | 2001-04-10 | — | — | US | claimed |
| EP-1032557-A1 | METHOD FOR PREPARING BROMOMETHYL-BIPHENYL DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2000-09-06 | — | — | EP | claimed |
| WO-1999025681-A1 | METHOD FOR PREPARING BROMOMETHYL-BIPHENYL DERIVATIVES | SANOFI-SYNTHELABO (FR) | 1999-05-27 | — | — | WO | claimed |
| EP-0553879-B1 | Process for producing 4-bromomethylbiphenyl compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-08-14 | — | — | EP | claimed |
| US-5312958-A | Process for producing 4-bromomethylbiphenyl compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-05-17 | — | — | US | claimed |
| EP-0553879-A2 | Process for producing 4-bromomethylbiphenyl compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-08-04 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12275734-B1 | Pleuromutilin onium salt derivative containing a 3H-imidazo[4,5-c]pyridine side chain, and a preparation method and application thereof | PLEC, PML, MRPL21 | ALDH1A1 2527/4885TSHR 1783/4885TRPA1 1822/4885 |
| US-12509426-B1 | Carbon-14 radioisotope-labeled flonicamid and synthesis method thereof | TMEM14C, RPL14, FOS | ALDH1A1 2800/4885TSHR 177/4885TRPA1 1737/4885 |
| US-20020095042-A1 | Process for brominating the side chain of 4-methylbiphenyl derivatives substituted in the 2' position | CBR1, CBR3, RCOR1 | ALDH1A1 1734/4885TSHR 411/4885TRPA1 3788/4885 |
| US-12304917-B1 | Pleuromutilin derivative containing a thiazolo[5,4-c]pyridine side chain, and a preparation method and application thereof | PLEC, MLN, MRPL21 | ALDH1A1 1092/4885TSHR 539/4885TRPA1 2341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.