Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14098172 | 0.84 | PLK1 (0.45) | PLK1MAOAMAOBLDHALDHB | |
| SCHEMBL7117517 | 0.82 | MAOA (0.43) | PLK1MAOAMAOBLDHALDHB | |
| SCHEMBL7110722 | 0.82 | CYP19A1 (0.48) | MAOAMAOBPOLBALDH1A1MEN1 | |
| SCHEMBL7112833 | 0.78 | MAOA (0.50) | PLK1MAOAMAOBLDHALDHB | |
| SCHEMBL7114519 | 0.78 | LDHA (0.43) | PLK1MAOAMAOBLDHALDHB | |
| SCHEMBL7110710 | 0.76 | MAOA (0.47) | MAOAMAOBTOP1TOP2AALDH1A1 | |
| SCHEMBL7115723 | 0.76 | ABCG2 (0.53) | MAOAMAOBABCG2ALDH1A1MAPT | |
| SCHEMBL7115666 | 0.72 | GAA (0.44) | MAOAMAOBPOLBABCG2NPC1 | |
| SCHEMBL7112829 | 0.71 | ALDH1A1 (0.49) | MAOAMAOBPOLBNPC1RAB9A | |
| SCHEMBL57888 | 0.70 | MAOA (0.62) | MAOAMAOBNPC1RAB9AACSL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065021-A1 | Tracheal smooth muscle relaxants | YAMASHITA SHINYA (JP) | 2003-04-03 | — | — | US | disclosed |
| US-6495592-B1 | DIBENZ(B,F)OXEPIN DERIVATIVES; ANTIASTHMATICS | NIPPON SUISAN KAISHA, LTD. (JP) | 2002-12-17 | — | — | US | disclosed |
| EP-0805155-B1 | NOVEL ANTIOXIDANT TRICYCLIC FUSED HETEROCYCLIC COMPOUND | NIPPON SUISAN KAISHA LTD (JP) | 2002-03-13 | — | — | EP | disclosed |
| US-6180659-B1 | USING A DIBENZO(B,F)-(OXEPIN OR THIEPIN) COMPOUND | NIPPON SUISAN KAISHA, LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-0885610-A1 | TRACHEAL SMOOTH MUSCLE RELAXANT | NIPPON SUISAN KAISHA, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0805155-A1 | NOVEL ANTIOXIDANT TRICYCLIC FUSED HETEROCYCLIC COMPOUND | NIPPON SUISAN KAISHA, LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065021-A1 | Tracheal smooth muscle relaxants | MYLK, MUSK, CPT1B | PLK1 4582/4885MAOA 2385/4885MAOB 2228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.