Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | BMP1 | P13497 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004439 | 0.90 | MEN1 (0.52) | MEN1KMT2ABMP1ALDH1A1MMP3 | |
| SCHEMBL7003884 | 0.83 | BMP1 (0.48) | MEN1KMT2ABMP1MMP3TAS2R14 | |
| SCHEMBL3621768 | 0.73 | SIGMAR1 (0.70) | MEN1KMT2AATMPLAAT3PLAAT5 | |
| SCHEMBL4614753 | 0.72 | MEN1 (0.71) | MEN1KMT2AALDH1A1POLBATM | |
| SCHEMBL28467893 | 0.71 | CA12 (0.60) | MEN1KMT2AATM | |
| SCHEMBL17372599 | 0.71 | NPC1 (0.65) | MEN1KMT2AALDH1A1ATMNPC1 | |
| SCHEMBL9372179 | 0.70 | SIGMAR1 (0.72) | MEN1KMT2AATM | |
| SCHEMBL6540208 | 0.70 | MEN1 (0.73) | MEN1KMT2AALDH1A1POLBATM | |
| SCHEMBL9487686 | 0.70 | MEN1 (0.60) | MEN1KMT2AALDH1A1POLBATM | |
| SCHEMBL8099595 | 0.70 | SIGMAR1 (0.68) | MEN1KMT2AALDH1A1ATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506936-B1 | Treating fibrotic disorder selected from hepatic cirrhosis and arthritis; inhibiting matrix metalloproteases | FIBROGEN, INC. | 2003-01-14 | — | — | US | claimed |
| US-20030191309-A1 | N-substituted arylsulfonylamino hydroxamic acids useful as inhibitors of C-proteinase and for treating or preventing disorders related to unregulated collagen production | HO WEN-BIN (US) | 2003-10-09 | — | — | US | disclosed |
| US-6506936-B1 | Treating fibrotic disorder selected from hepatic cirrhosis and arthritis; inhibiting matrix metalloproteases | FIBROGEN, INC. | 2003-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191309-A1 | N-substituted arylsulfonylamino hydroxamic acids useful as inhibitors of C-proteinase and for treating or preventing disorders related to unregulated collagen production | MMP1, MMP13, COL14A1 | MEN1 4787/4885KMT2A 1817/4885BMP1 730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.