Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27431134 | 1.00 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL7111645 | 0.93 | — | — | |
| SCHEMBL12118788 | 0.83 | TSHR (0.40) | MEN1KMT2A | |
| SCHEMBL567667 | 0.83 | TSHR (0.40) | MEN1KMT2A | |
| SCHEMBL8012777 | 0.83 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL3839822 | 0.77 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL219412 | 0.77 | ALDH1A1 (0.40) | MEN1KMT2A | |
| SCHEMBL2739848 | 0.76 | — | — | |
| SCHEMBL390230 | 0.76 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL28647211 | 0.76 | MEN1 (0.38) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586644-B2 | Reacting aldehyde compound and terminal acetylene in presence of optically active amino alcohol, using tertiary amine and zinc halogenated lower alkane sulfonate as catalyst | Carreira, Erick M. (CH) | 2003-07-01 | — | — | US | claimed |
| US-20030088100-A1 | Process for producing optically active propargyl alcohols | SUMIKA FINE CHEMICALS CO., LTD. | 2003-05-08 | — | — | US | claimed |
| CN-107922379-B | Substituted guanidine derivatives | 宇部兴产株式会社 | 2020-11-06 | — | — | CN | disclosed |
| US-10759781-B2 | Substituted guanidine derivatives | UBE INDUSTRIES, LTD. (JP) | 2020-09-01 | — | — | US | disclosed |
| US-20190152953-A1 | SUBSTITUTED GUANIDINE DERIVATIVES | UBE INDUSTRIES, LTD. (JP) | 2019-05-23 | — | — | US | disclosed |
| EP-3333163-A1 | SUBSTITUTED GUANIDINE DERIVATIVE | UBE Industries, Ltd. (JP) | 2018-06-13 | — | — | EP | disclosed |
| US-6586644-B2 | Reacting aldehyde compound and terminal acetylene in presence of optically active amino alcohol, using tertiary amine and zinc halogenated lower alkane sulfonate as catalyst | Carreira, Erick M. (CH) | 2003-07-01 | — | — | US | disclosed |
| US-20030088100-A1 | Process for producing optically active propargyl alcohols | SUMIKA FINE CHEMICALS CO., LTD. | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030088100-A1 | Process for producing optically active propargyl alcohols | ADH1A, ADH1C, ADH5 | MEN1 4339/4885KMT2A 1721/4885 |
| US-10759781-B2 | Substituted guanidine derivatives | GMPS, GUCY1A1, GUCY1A2 | MEN1 1957/4885KMT2A 2982/4885 |
| US-20190152953-A1 | SUBSTITUTED GUANIDINE DERIVATIVES | GMPS, GUCY1A1, GUCY1A2 | MEN1 1957/4885KMT2A 2982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.