Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711444 | 1.00 | CHEK2 (0.35) | CHEK2AURKBHPGD | |
| SCHEMBL711443 | 0.85 | KDM4E (0.39) | HPGD | |
| SCHEMBL651235 | 0.78 | HPGD (0.42) | CHEK2AURKBHPGD | |
| SCHEMBL651233 | 0.78 | HPGD (0.42) | CHEK2AURKBHPGD | |
| SCHEMBL708159 | 0.72 | PIK3CA (0.35) | — | |
| SCHEMBL710607 | 0.70 | MAPT (0.34) | HPGD | |
| SCHEMBL710608 | 0.70 | MAPT (0.34) | HPGD | |
| SCHEMBL705496 | 0.68 | PIK3CA (0.37) | — | |
| SCHEMBL6608189 | 0.65 | LTA4H (0.49) | CHEK2AURKB | |
| SCHEMBL708157 | 0.65 | SYK (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |