Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31634590 | 1.00 | CASP7 (0.47) | CASP7G6PDCASP6CA12CA1 | |
| SCHEMBL16431370 | 0.86 | CA1 (0.54) | CASP7G6PDCASP6CA12CA1 | |
| SCHEMBL1000209 | 0.85 | KMT2A (0.44) | CASP7G6PDCASP6CA12CA1 | |
| SCHEMBL15439886 | 0.84 | CA12 (0.52) | CASP7G6PDCASP6CA12CA1 | |
| SCHEMBL13202508 | 0.82 | SELL (0.46) | CASP7G6PDCASP6CA12CA1 | |
| SCHEMBL9490123 | 0.80 | CASP7 (0.55) | CASP7G6PDCASP6CA12CA1 | |
| SCHEMBL3822164 | 0.80 | KMT2A (0.48) | CASP6CA12CA1CA2CA7 | |
| SCHEMBL31348929 | 0.80 | KMT2A (0.48) | CASP6CA12CA1CA2CA7 | |
| SCHEMBL9719338 | 0.79 | MAPT (0.50) | CASP7G6PDCASP6KMT2AMEN1 | |
| SCHEMBL24752830 | 0.78 | KEAP1 (0.42) | CASP7G6PDCASP6CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030109682-A1 | Maytansines and maytansine conjugates | SANTI DANIEL (US) | 2003-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109682-A1 | Maytansines and maytansine conjugates | AREG, HDGF, GHITM | CASP7 512/4885G6PD 614/4885CASP6 1198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.