Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27894750 | 0.85 | CA12 (0.43) | MAPTALDH1A1POLBHTTHSD17B10 | |
| SCHEMBL28135536 | 0.83 | ALDH1A1 (0.62) | MAPTGAAALDH1A1POLBHTT | |
| SCHEMBL27894749 | 0.82 | PBRM1 (0.56) | ALDH1A1POLBHSD17B10PBRM1LMNA | |
| SCHEMBL9833894 | 0.81 | CNR2 (0.45) | MAPTGAAALDH1A1HSD17B10PBRM1 | |
| SCHEMBL28147122 | 0.81 | CASP7 (0.52) | MAPTGAAALDH1A1POLBHTT | |
| SCHEMBL10963218 | 0.81 | MAPT (0.60) | MAPTGAAALDH1A1POLBHTT | |
| SCHEMBL31634590 | 0.79 | CASP7 (0.47) | MAPTGAAALDH1A1POLBHSD17B10 | |
| SCHEMBL7115336 | 0.79 | CASP7 (0.47) | MAPTGAAALDH1A1POLBHSD17B10 | |
| SCHEMBL11869293 | 0.78 | MAPT (0.57) | MAPTGAAALDH1A1POLBHTT | |
| SCHEMBL11858611 | 0.77 | MAPT (0.65) | MAPTGAAALDH1A1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3200752-A | — | — | None | — | — | JP | disclosed |
| US-5130481-A | BIS-N,N' NITRO OR AMINO BENZOYL AMINO PHENOLS | HOECHST CELANESE CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |
| JP-H03200752-A | BIS-N,N' NITRO OR AMINO BENZOYL AMINO PHENOL | HOECHST CELANESE CORP | 1991-09-02 | — | — | JP | disclosed |
| EP-0387060-A3 | BIS-N,N' NITRO OR AMINO BENZOYL AMINOPHENOLS | HOECHST CELANESE CORPORATION (US) | 1991-06-12 | — | — | EP | disclosed |
| EP-0387060-A2 | Bis-N,N' nitro or amino benzoyl aminophenols | HOECHST CELANESE CORPORATION (US) | 1990-09-12 | — | — | EP | disclosed |