SCHEMBL7116752

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7114083	0.86	KDM4E (0.36)	HPGDKDM4EGAAALDH1A1MEN1
	SCHEMBL7120967	0.81	SIRT1 (0.42)	SIRT1LMNAHPGDKDM4EALDH1A1
	SCHEMBL7114050	0.78	PDE9A (0.44)	SIRT1LMNAHPGDKDM4ECYP1A2
	SCHEMBL7121233	0.75	SIRT1 (0.42)	SIRT1LMNAALDH1A1CSF1RMEN1
	SCHEMBL7549488	0.72	TNKS (0.32)	PARP1
	SCHEMBL7122454	0.71	GRIN2D (0.58)	SIRT1LMNAHPGDKDM4ECYP1A2
	SCHEMBL7114324	0.70	MPO (0.37)	HPGDKDM4EGAAALDH1A1MEN1
	SCHEMBL7121433	0.70	CSF1R (0.39)	SIRT1LMNAHPGDCYP1A2GAA
	SCHEMBL7121250	0.68	TSHR (0.41)	HPGDKDM4EALDH1A1MEN1MAPT
	SCHEMBL13390923	0.67	CSF1R (0.65)	KDM4EALDH1A1CSF1RMAPTROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.