Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.59 |
| ▸ | HTT | P42858 | 10/20 | 0.59 |
| ▸ | RAB9A | P51151 | 10/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 9/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | ATM | Q13315 | 5/20 | 0.59 |
| ▸ | CDC25A | P30304 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | CDC25B | P30305 | 3/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.59 |
| ▸ | NSD2 | O96028 | 2/20 | 0.59 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MITF | O75030 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506683 | 0.75 | MAPT (1.00) | MAPTHTTRAB9ANPSR1KMT2A | |
| SCHEMBL29633261 | 0.75 | MAPT (1.00) | MAPTHTTRAB9ANPSR1KMT2A | |
| SCHEMBL5808588 | 0.75 | MAPT (0.68) | MAPTHTTRAB9ANPSR1KMT2A | |
| SCHEMBL22212561 | 0.71 | MAPT (0.54) | MAPTHTTRAB9ANPSR1KMT2A | |
| SCHEMBL12352053 | 0.70 | KMT2A (0.55) | MAPTHTTRAB9ANPSR1KMT2A | |
| SCHEMBL2241338 | 0.70 | ALDH1A1 (0.59) | MAPTHTTRAB9ANPSR1KMT2A | |
| SCHEMBL8663288 | 0.69 | MAPT (0.74) | MAPTHTTRAB9ANPSR1KMT2A | |
| SCHEMBL4873496 | 0.69 | MAPT (1.00) | MAPTHTTRAB9ANPSR1KMT2A | |
| SCHEMBL12283051 | 0.69 | MAPT (0.72) | MAPTHTTRAB9ANPSR1KMT2A | |
| SCHEMBL32664539 | 0.69 | MAPT (0.79) | MAPTHTTRAB9ANPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793656-B1 | NOVEL BENZYL PYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2003-03-26 | — | — | EP | disclosed |
| US-5763450-A | BACTERICIDES; TREATMENT OF INFECTIOUS DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0793656-A1 | NOVEL BENZYL PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996016046-A2 | NOVEL BENZYL PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-05-30 | — | — | WO | disclosed |