SCHEMBL5808588

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7240445	0.82	MAPT (0.74)	MAPTRAB9AHTTKMT2ANPSR1
	SCHEMBL29633261	0.81	MAPT (1.00)	MAPTRAB9AHTTKMT2ANPSR1
	SCHEMBL6506683	0.81	MAPT (1.00)	MAPTRAB9AHTTKMT2ANPSR1
	SCHEMBL24327533	0.78	MAPT (0.44)	MAPTRAB9AHTTKMT2ANPSR1
	SCHEMBL1243522	0.78	MAPT (0.73)	MAPTRAB9AHTTKMT2ANPSR1
	SCHEMBL11786902	0.76	GNG2 (0.67)	MAPTKMT2AMEN1MAPK1LMNA
	SCHEMBL32664539	0.75	MAPT (0.79)	MAPTRAB9AHTTKMT2ANPSR1
	SCHEMBL31682570	0.75	RAB9A (0.62)	MAPTRAB9AHTTKMT2ANPSR1
	SCHEMBL7118329	0.75	MAPT (0.59)	MAPTRAB9AHTTKMT2ANPSR1
	SCHEMBL1242311	0.74	MAPT (0.67)	MAPTRAB9AHTTKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.