Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18617684 | 0.79 | MAPT (0.48) | ALDH1A1MAPTKMT2APOLBMEN1 | |
| SCHEMBL2340487 | 0.79 | MAPT (0.48) | ALDH1A1MAPTKMT2APOLBMEN1 | |
| SCHEMBL8596016 | 0.79 | MAPT (0.48) | ALDH1A1MAPTKMT2APOLBMEN1 | |
| SCHEMBL25846851 | 0.79 | LOXL2 (0.52) | ALDH1A1MAPTKMT2APOLBMEN1 | |
| SCHEMBL3820241 | 0.79 | MAPT (0.48) | ALDH1A1MAPTKMT2APOLBMEN1 | |
| SCHEMBL30002633 | 0.79 | MAPT (0.48) | ALDH1A1MAPTKMT2APOLBMEN1 | |
| SCHEMBL11306631 | 0.77 | KDM4E (0.33) | MAPTKMT2AKDM4ELMNAHTT | |
| SCHEMBL24788998 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2APOLBMEN1 | |
| SCHEMBL17241883 | 0.76 | MAPT (0.46) | ALDH1A1MAPTKMT2APOLBMEN1 | |
| SCHEMBL27328329 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6573379-B2 | Contacting 6-methyl quinoxaline with N- bromosuccinimide in the presence of a radical initiator in 1, 2-dichloroethane to form 6-bromomethyl quinoxaline | AIR PRODUCTS AND CHEMICALS, INC. | 2003-06-03 | — | — | US | disclosed |
| US-20030050475-A1 | Method for preparing halomethyl heterocyclic compounds | BURDENIUC JUAN JESUS (US) | 2003-03-13 | — | — | US | disclosed |
| EP-1277742-A1 | Method for preparing halomethyl heterocyclic compounds | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2003-01-22 | — | — | EP | disclosed |
| US-6492517-B1 | THE PRESENT INVENTION RELATES TO A METHOD FOR PREPARING 5- AND 6-HALOMETHYL QUINOXALINES IN PRESENCE OF A RADICAL INITIATOR IN A SOLVENT SELECTED FROM THE GROUP CONSISTING OF FLUOROBENZENE, DIFLUOROBENZENES, TRIFLUOROBENZENES, | AIR PRODUCTS AND CHEMICALS, INC. | 2002-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030050475-A1 | Method for preparing halomethyl heterocyclic compounds | HDHD5, HNMT, CBR3 | ALDH1A1 2209/4885MAPT 4742/4885KMT2A 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.