Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9911118 | 0.86 | LOXL2 (0.41) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL31374504 | 0.86 | LOXL2 (0.41) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL24788998 | 0.84 | ALDH1A1 (0.46) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2340487 | 0.79 | MAPT (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL30002633 | 0.79 | MAPT (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL18617684 | 0.79 | MAPT (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7119359 | 0.79 | ALDH1A1 (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL25846851 | 0.79 | LOXL2 (0.52) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3820241 | 0.79 | MAPT (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL21037109 | 0.79 | GABRA1 (0.47) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002407-A1 | COT MODULATORS AND METHODS OF USE THEREOF | GILEAD SCIENCES, INC. | 2023-01-05 | — | — | US | disclosed |
| US-11266643-B2 | Triaryl compounds for treatment of PD-L1 diseases | CHEMOCENTRYX, INC. (US) | 2022-03-08 | — | — | US | disclosed |
| US-10981907-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-04-20 | — | — | US | disclosed |
| US-20200392170-A1 | COT MODULATORS AND METHODS OF USE THEREOF | GILEAD SCIENCES, INC. | 2020-12-17 | — | — | US | disclosed |
| WO-2020232256-A1 | TRIARYL COMPOUNDS FOR TREATMENT OF PD-L1 DISEASES | CHEMOCENTRYX, INC. (US) | 2020-11-19 | — | — | WO | disclosed |
| US-10736320-B2 | Pesticidally active polycyclic derivatives with 5-membered sulfur containing heterocyclic ring systems | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-11 | — | — | US | disclosed |
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | US | disclosed |
| US-10590123-B2 | Pesticidally active amide heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-03-17 | — | — | US | disclosed |
| US-10544148-B2 | Pesticidally active tetracyclic heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-01-28 | — | — | US | disclosed |
| US-10512265-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2019-12-24 | — | — | US | disclosed |
| WO-2016120182-A1 | PESTICIDALLY ACTIVE AMIDE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-04 | — | — | WO | disclosed |
| US-20150191432-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-07-09 | — | — | US | disclosed |
| US-20140284581-A1 | ORGANIC LIGHT EMITTING HOST MATERIALS | NITTO DENKO CORPORATION (JP) | 2014-09-25 | — | — | US | disclosed |
| WO-2014135107-A1 | NOVEL NUCLEOSIDE PHOSPHORAMIDATE COMPOUND AND USE THEREOF | 南京圣和药业有限公司 (CN) | 2014-09-12 | — | — | WO | disclosed |
| US-20100056530-A1 | GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2010-03-04 | — | — | US | disclosed |
| US-20080312435-A1 | Imine Compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-12-18 | — | — | US | disclosed |
| WO-2008082484-A1 | 4,5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2008-07-10 | — | — | WO | disclosed |
| US-20070225292-A1 | Therapeutic Compounds: Pyridine as Scaffold | ASTRAZENECA AB (SE) | 2007-09-27 | — | — | US | disclosed |
| US-20070219254-A1 | Therapeutic Compounds: Pyridine N-Oxide Scaffold | ASTRAZENECA AB (SE) | 2007-09-20 | — | — | US | disclosed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312435-A1 | Imine Compound | CNR1, CNR2, HRH4 | MAPT 4160/4885ALDH1A1 2674/4885MEN1 761/4885 |
| US-20200392170-A1 | COT MODULATORS AND METHODS OF USE THEREOF | BRDT, THRB, HCCS | MAPT 4689/4885ALDH1A1 2149/4885MEN1 1719/4885 |
| US-10544148-B2 | Pesticidally active tetracyclic heterocyclic derivatives with sulphur containing substituents | DDT, ACHE, TST | MAPT 1046/4885ALDH1A1 433/4885MEN1 1558/4885 |
| US-10981907-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | DDT, ACHE, GSTM1 | MAPT 336/4885ALDH1A1 1216/4885MEN1 996/4885 |
| US-10590123-B2 | Pesticidally active amide heterocyclic derivatives with sulphur containing substituents | DDT, ACHE, GSTM1 | MAPT 561/4885ALDH1A1 443/4885MEN1 2161/4885 |
| US-20150191432-A1 | PRMT5 INHIBITORS AND USES THEREOF | PRMT5, PRMT1, PRMT6 | MAPT 2923/4885ALDH1A1 2460/4885MEN1 1329/4885 |
| US-20230002407-A1 | COT MODULATORS AND METHODS OF USE THEREOF | BRDT, THRB, HCCS | MAPT 4689/4885ALDH1A1 2149/4885MEN1 1719/4885 |
| US-10512265-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | DDT, ACHE, GSTM1 | MAPT 661/4885ALDH1A1 354/4885MEN1 1431/4885 |
| US-20070219254-A1 | Therapeutic Compounds: Pyridine N-Oxide Scaffold | OPRM1, OPRL1, OPRD1 | MAPT 1380/4885ALDH1A1 965/4885MEN1 2768/4885 |
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | MAPT 2188/4885ALDH1A1 344/4885MEN1 4127/4885 |
| US-20070225292-A1 | Therapeutic Compounds: Pyridine as Scaffold | OPRL1, OPRK1, P2RX3 | MAPT 802/4885ALDH1A1 692/4885MEN1 3429/4885 |
| US-10736320-B2 | Pesticidally active polycyclic derivatives with 5-membered sulfur containing heterocyclic ring systems | DDT, TST, GSS | MAPT 681/4885ALDH1A1 1564/4885MEN1 785/4885 |
| US-20100056530-A1 | GLUCOKINASE ACTIVATORS | GCKR, GCK, GALK1 | MAPT 4558/4885ALDH1A1 1377/4885MEN1 3117/4885 |
| US-11266643-B2 | Triaryl compounds for treatment of PD-L1 diseases | CD274, PDCD1, PDCD1LG2 | MAPT 2969/4885ALDH1A1 380/4885MEN1 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.