Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | LMNA | P02545 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | SLC10A6 | Q3KNW5 | 2/20 | 0.65 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.65 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 6/20 | 0.63 |
| ▸ | RECQL | P46063 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214479 | 0.96 | SLC10A6 (0.72) | SMN1; SMN2KMT2ALMNAMEN1MAPT | |
| SCHEMBL7213170 | 0.93 | MEN1 (0.76) | SMN1; SMN2KMT2ALMNAMEN1MAPT | |
| SCHEMBL7208737 | 0.86 | MEN1 (0.67) | SMN1; SMN2KMT2ALMNAMEN1MAPT | |
| SCHEMBL492639 | 0.85 | SLC10A6 (0.56) | SMN1; SMN2KMT2ALMNAMEN1MAPT | |
| SCHEMBL7213034 | 0.84 | MEN1 (0.57) | SMN1; SMN2KMT2ALMNAMEN1MAPT | |
| SCHEMBL492766 | 0.82 | SLC10A2 (0.52) | SMN1; SMN2KMT2ALMNAMEN1MAPT | |
| SCHEMBL492769 | 0.82 | SLC10A2 (0.52) | SMN1; SMN2KMT2ALMNAMEN1MAPT | |
| SCHEMBL7127128 | 0.81 | SLC10A2 (0.60) | KMT2ALMNAMEN1MAPTSLC10A6 | |
| SCHEMBL27561779 | 0.80 | SLC10A6 (0.50) | SMN1; SMN2KMT2ALMNAMEN1MAPT | |
| SCHEMBL7116008 | 0.80 | SLC10A6 (0.85) | KMT2ALMNAMEN1MAPTSLC10A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216449-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-20 | — | — | US | claimed |
| CN-1429108-A | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORP (US) | 2003-07-09 | — | — | CN | claimed |
| EP-1202729-A1 | PHOSPHATE TRANSPORT INHIBITORS | SmithKline Beecham Corporation (US) | 2002-05-08 | — | — | EP | claimed |
| WO-2001087294-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |
| WO-2001005398-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-01-25 | — | — | WO | claimed |
| US-20030216449-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-20 | — | — | US | disclosed |
| US-20030212074-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-13 | — | — | US | disclosed |
| CN-1429108-A | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORP (US) | 2003-07-09 | — | — | CN | disclosed |
| EP-1202729-A1 | PHOSPHATE TRANSPORT INHIBITORS | SmithKline Beecham Corporation (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |
| WO-2001087294-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-22 | — | — | WO | disclosed |
| WO-2001082924-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |
| WO-2001005398-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216449-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC34A3 | SMN1; SMN2 4142/4885KMT2A 4033/4885LMNA 4639/4885 |
| US-20030212074-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A3, SLC34A1 | SMN1; SMN2 4632/4885KMT2A 3005/4885LMNA 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.