Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504020 | 0.73 | LMNA (0.50) | ALOX5APFEN1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL29693606 | 0.73 | LMNA (0.50) | ALOX5APFEN1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL13351700 | 0.69 | MAPT (0.41) | CYP3A4ALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL8788979 | 0.68 | ALOX5AP (0.38) | ALOX5APFEN1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL20606895 | 0.65 | ALDH1A1 (0.44) | POLBCYP1A2CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL13713702 | 0.64 | LMNA (0.44) | ALDH1A1LMNAATML3MBTL1 | |
| SCHEMBL6335755 | 0.63 | LMNA (0.43) | CYP1A2CYP3A4ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL10398846 | 0.63 | CDK1 (0.43) | POLBCYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL28281923 | 0.63 | NUDT1 (0.41) | POLBALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL11462527 | 0.63 | PIM1 (0.40) | CYP3A4ALDH1A1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030114414-A1 | Methods for synthesizing substituted pyrimidines | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2003-06-19 | — | — | US | disclosed |
| WO-2002102769-A2 | METHODS FOR SYNTHESIZING SUBSTITUTED PYRIMIDINES | UNIVERSITY OF MASSACHUSETTS (US) | 2002-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114414-A1 | Methods for synthesizing substituted pyrimidines | TYMP, NUDT1, TYMS | LTB4R 2366/4885POLB 49/4885ALOX5AP 1258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.