Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129076 | 0.92 | SMYD3 (0.35) | SMYD3NOD2NOD1MAPK14SMN1; SMN2 | |
| SCHEMBL7129797 | 0.87 | MAPK14 (0.32) | SMYD3NOD2NOD1MAPK14HSD17B3 | |
| Trifluoroacetic Acid SCHEMBL7426138 | 0.79 | OPRM1 (0.35) | — | |
| Trifluoroacetic Acid SCHEMBL7128334 | 0.79 | OPRM1 (0.34) | — | |
| Trifluoroacetic Acid SCHEMBL7129463 | 0.70 | ACHE (0.35) | — | |
| SCHEMBL7121817 | 0.70 | HSD17B3 (0.41) | HSD17B3 | |
| SCHEMBL7131862 | 0.68 | RXRA (0.36) | SMYD3MAPK14HSD17B3SMN1; SMN2ALDH1A1 | |
| SCHEMBL4805867 | 0.68 | MAPT (0.38) | SMYD3NOD2NOD1MAPK14TRPC6 | |
| Hydrochloric Acid SCHEMBL7128388 | 0.68 | RXRA (0.36) | MAPK14HSD17B3SMN1; SMN2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7427799 | 0.68 | MAPK14 (0.36) | SMYD3MAPK14HSD17B3SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294691-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096305-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2001-12-20 | — | — | WO | disclosed |