Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4803612 | 0.86 | TPSAB1 (0.41) | OPRM1OPRD1OPRK1F10 | |
| SCHEMBL4813549 | 0.81 | SMYD3 (0.38) | OPRM1OPRD1OPRK1CHRM2CHRM3 | |
| Trifluoroacetic Acid SCHEMBL4810746 | 0.78 | F2 (0.38) | OPRM1OPRD1OPRK1UBE2MDCUN1D1 | |
| SCHEMBL4812628 | 0.77 | GPR119 (0.42) | — | |
| SCHEMBL4810407 | 0.76 | OPRM1 (0.42) | HSD17B3OPRM1OPRD1OPRK1MCHR1 | |
| Trifluoroacetic Acid SCHEMBL7434362 | 0.76 | OPRM1 (0.37) | OPRM1OPRD1F10 | |
| Trifluoroacetic Acid SCHEMBL4807393 | 0.73 | AGER (0.39) | — | |
| Trifluoroacetic Acid SCHEMBL4810923 | 0.71 | DCUN1D1 (0.36) | OPRM1OPRD1DCUN1D1F10 | |
| Trifluoroacetic Acid SCHEMBL7433732 | 0.70 | SLC6A2 (0.34) | OPRM1OPRD1 | |
| SCHEMBL7121914 | 0.70 | SMYD3 (0.35) | HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294691-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2003-03-26 | — | — | EP | disclosed |
| EP-1240154-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001096305-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2001-12-20 | — | — | WO | disclosed |
| WO-2001044226-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2001-06-21 | — | — | WO | disclosed |