Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.33 |
| ▸ | CPS1 | P31327 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7426138 | 0.79 | OPRM1 (0.35) | OPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL7128334 | 0.78 | OPRM1 (0.34) | OPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL7423644 | 0.77 | ACHE (0.39) | ACHEOPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL5210906 | 0.75 | ACHE (0.39) | ACHEOPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL6486974 | 0.71 | ACHE (0.38) | ACHEOPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL4807063 | 0.71 | ACHE (0.34) | ACHE | |
| SCHEMBL7129797 | 0.71 | MAPK14 (0.32) | — | |
| SCHEMBL7121914 | 0.70 | SMYD3 (0.35) | — | |
| SCHEMBL6995003 | 0.70 | NPC1 (0.39) | — | |
| Trifluoroacetic Acid SCHEMBL5216054 | 0.70 | ACHE (0.38) | ACHEOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294691-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096305-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2001-12-20 | — | — | WO | disclosed |