Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209028 | 1.00 | SLC15A1 (0.43) | SLC15A1ALDH1A1HDAC6CCNT1CDK9 | |
| SCHEMBL7734416 | 1.00 | SLC15A1 (0.43) | SLC15A1ALDH1A1HDAC6CCNT1CDK9 | |
| SCHEMBL7740690 | 0.90 | SLC15A1 (0.41) | SLC15A1ALDH1A1HDAC6CCNT1CDK9 | |
| SCHEMBL9419631 | 0.89 | HDAC6 (0.35) | SLC15A1ALDH1A1HDAC6CCNT1CDK9 | |
| SCHEMBL9387641 | 0.89 | HDAC6 (0.35) | SLC15A1ALDH1A1HDAC6CCNT1CDK9 | |
| SCHEMBL9419671 | 0.89 | HDAC6 (0.35) | SLC15A1ALDH1A1HDAC6CCNT1CDK9 | |
| SCHEMBL7734546 | 0.87 | ALDH1A1 (0.41) | SLC15A1ALDH1A1LMNATP53MAPT | |
| SCHEMBL7734335 | 0.87 | ALDH1A1 (0.35) | SLC15A1ALDH1A1ADORA2BLMNATP53 | |
| SCHEMBL7734321 | 0.87 | ADORA2B (0.35) | SLC15A1ALDH1A1ADORA2B | |
| SCHEMBL7734412 | 0.86 | ALDH1A1 (0.38) | SLC15A1ALDH1A1LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970100-B1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-11-12 | — | — | EP | disclosed |
| US-6617315-B1 | Sugar-substituted benzimidazole derivatives are used for the treatment or prophylaxis of restenosis, particularly following angioplasty | CHAMBERLAIN STANLEY DAWES (US) | 2003-09-09 | — | — | US | disclosed |
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |
| US-6204249-B1 | L-benzimidazole nucleosides | GLAXO WELLCOME INC. | 2001-03-20 | — | — | US | disclosed |
| EP-0970100-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998035977-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |