Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734412 | 0.93 | ALDH1A1 (0.38) | ALDH1A1SLC15A1LMNATP53MAPT | |
| SCHEMBL7741960 | 0.89 | ALDH1A1 (0.34) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL7209028 | 0.87 | SLC15A1 (0.43) | ALDH1A1SLC15A1LMNATP53MAPT | |
| SCHEMBL7734416 | 0.87 | SLC15A1 (0.43) | ALDH1A1SLC15A1LMNATP53MAPT | |
| SCHEMBL7123962 | 0.87 | SLC15A1 (0.43) | ALDH1A1SLC15A1LMNATP53MAPT | |
| SCHEMBL7738765 | 0.84 | ALDH1A1 (0.33) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL7734321 | 0.81 | ADORA2B (0.35) | ALDH1A1SLC15A1 | |
| SCHEMBL7734335 | 0.79 | ALDH1A1 (0.35) | ALDH1A1SLC15A1LMNATP53MAPT | |
| SCHEMBL7740690 | 0.78 | SLC15A1 (0.41) | ALDH1A1SLC15A1 | |
| SCHEMBL9419671 | 0.78 | HDAC6 (0.35) | ALDH1A1SLC15A1LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |