Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734321 | 0.92 | ADORA2B (0.35) | ALDH1A1SLC15A1ADORA2BKMT2AKDM4E | |
| SCHEMBL7123962 | 0.87 | SLC15A1 (0.43) | ALDH1A1SLC15A1TP53ADORA2BLMNA | |
| SCHEMBL7734416 | 0.87 | SLC15A1 (0.43) | ALDH1A1SLC15A1TP53ADORA2BLMNA | |
| SCHEMBL7209028 | 0.87 | SLC15A1 (0.43) | ALDH1A1SLC15A1TP53ADORA2BLMNA | |
| SCHEMBL7114061 | 0.85 | CYP11B2 (0.34) | ALDH1A1SLC15A1HPGDKDM4E | |
| SCHEMBL6956240 | 0.83 | POLB (0.44) | ALDH1A1SLC15A1ADORA2BADORA1LMNA | |
| SCHEMBL7734546 | 0.79 | ALDH1A1 (0.41) | ALDH1A1SLC15A1TP53LMNAMAPT | |
| SCHEMBL7111753 | 0.78 | USP2 (0.39) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7740660 | 0.78 | ALDH1A1 (0.40) | ALDH1A1TP53LMNAMAPTTDP1 | |
| SCHEMBL7734412 | 0.78 | ALDH1A1 (0.38) | ALDH1A1SLC15A1TP53LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |
| EP-0970100-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998035977-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |