Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GLA | P06280 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116680 | 0.83 | NCF1 (0.53) | LMNAPOLBMAPTHTTKMT2A | |
| SCHEMBL9296399 | 0.80 | HTR3A (0.43) | ACHEHSD17B10KDM4EALDH1A1GLA | |
| SCHEMBL3143334 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL4163816 | 0.75 | PSMB8 (0.39) | ACHEHSD17B10KDM4EALDH1A1GLA | |
| SCHEMBL3259839 | 0.72 | ALDH1A1 (0.52) | HSD17B10KDM4EALDH1A1CASP1SMN1; SMN2 | |
| Ethylenediamine SCHEMBL9297163 | 0.71 | ALOX12 (0.30) | PARL | |
| Acridine SCHEMBL7872845 | 0.70 | ALDH1A1 (0.46) | ACHEKDM4EALDH1A1GLAHPGD | |
| SCHEMBL16261005 | 0.68 | NPC1 (0.50) | SMN1; SMN2ADORA3RAB9AMAPTKMT2A | |
| SCHEMBL1205198 | 0.68 | SMN1; SMN2 (0.51) | ACHEKDM4EALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL9296664 | 0.68 | PARP1 (0.35) | HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6632629-B2 | Microfluidic in-line labeling method of continuous-flow protease inhibition analysis | CALIPER TECHNOLOGIES CORP. | 2003-10-14 | — | — | US | claimed |
| US-20030064425-A1 | Microfluidic in-line labeling method for continuous-flow protease inhibition analysis | CALIPER TECHNOLOGIES CORP. | 2003-04-03 | — | — | US | claimed |
| US-6468761-B2 | Microfluidic in-line labeling method for continuous-flow protease inhibition analysis | CALIPER TECHNOLOGIES, CORP. | 2002-10-22 | — | — | US | claimed |
| US-20010026929-A1 | Microfluidic in-line labeling method for continuous-flow protease inhibition analysis | CALIPER TECHNOLOGIES CORP. | 2001-10-04 | — | — | US | claimed |
| EP-0533200-A1 | Preparation and use of novel activated carbamates | WATERS INVESTMENTS LIMITED (US) | 1993-03-24 | — | — | EP | claimed |
| US-6632629-B2 | Microfluidic in-line labeling method of continuous-flow protease inhibition analysis | CALIPER TECHNOLOGIES CORP. | 2003-10-14 | — | — | US | disclosed |
| US-20030064425-A1 | Microfluidic in-line labeling method for continuous-flow protease inhibition analysis | CALIPER TECHNOLOGIES CORP. | 2003-04-03 | — | — | US | disclosed |
| US-6468761-B2 | Microfluidic in-line labeling method for continuous-flow protease inhibition analysis | CALIPER TECHNOLOGIES, CORP. | 2002-10-22 | — | — | US | disclosed |
| US-20010026929-A1 | Microfluidic in-line labeling method for continuous-flow protease inhibition analysis | CALIPER TECHNOLOGIES CORP. | 2001-10-04 | — | — | US | disclosed |
| US-5296599-A | Activated carbamates compounds | MILLIPORE CORPORATION (US) | 1994-03-22 | — | — | US | disclosed |
| EP-0533200-A1 | Preparation and use of novel activated carbamates | WATERS INVESTMENTS LIMITED (US) | 1993-03-24 | — | — | EP | disclosed |