SCHEMBL7124720

SCHEMBL7124720

Cc1noc(-c2ccccc2)c1C(=O)[AsH]c1cccc2cc(C(=O)Nc3ccc(C#N)cc3C(=O)O)[nH]c12

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.41
ALDH1A1 P00352 4/20 0.36
POLB P06746 2/20 0.36
NSD2 O96028 1/20 0.35
ALB P02768 1/20 0.34
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PIN1 Q13526 1/20 0.33
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NHERF1 O14745 1/20 0.32
NR1H4 Q96RI1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6830653 0.89 TRPA1 (0.47) TRPA1ALDH1A1POLBNSD2ALB
SCHEMBL7131750 0.76 POLB (0.42) POLBNSD2ALBMEN1KMT2A
SCHEMBL6818302 0.76 NSD2 (0.58) POLBNSD2ALBMEN1KMT2A
SCHEMBL6710153 0.76 TRPA1 (0.43) TRPA1ALDH1A1POLBNSD2GSK3A
SCHEMBL6833424 0.76 TDP1 (0.46) ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL6713877 0.75 TRPA1 (0.43) TRPA1ALDH1A1POLBNSD2GSK3A
SCHEMBL6834385 0.75 SERPINE1 (0.51) ALBKMT2ANHERF1NR1H4
SCHEMBL6834154 0.73 KMT2A (0.49) ALBMEN1KMT2ANHERF1NR1H4
SCHEMBL6833137 0.73 MAP3K5 (0.44) POLBNSD2ALBKMT2ANHERF1
SCHEMBL6830559 0.72 NHERF1 (0.45) NSD2ALBNHERF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004018428-A1 ANTIBACTERIAL BENZOIC ACID DERIVATIVES PHARMACIA & UPJOHN COMPANY LLC (US) 2004-03-04 WO disclosed