Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6917237 | 0.89 | HTR6 (0.39) | HTR6CYP19A1CNR2LMNAFNTA | |
| SCHEMBL6817354 | 0.76 | HTR7 (0.48) | HTR6CYP19A1LMNAIDO1ALDH1A1 | |
| SCHEMBL6919899 | 0.75 | HTR6 (0.43) | HTR6LMNAIDO1ALDH1A1 | |
| SCHEMBL6917789 | 0.74 | MEN1 (0.35) | ALDH1A1TSHRGSK3B | |
| SCHEMBL7130815 | 0.72 | ELANE (0.47) | HTR6ALDH1A1TSHR | |
| SCHEMBL3252401 | 0.71 | HTR6 (0.44) | HTR6CYP19A1LMNAFNTAFNTB | |
| SCHEMBL3264614 | 0.71 | HTR6 (0.54) | HTR6CYP19A1 | |
| SCHEMBL28751628 | 0.70 | HTR6 (0.42) | HTR6CYP19A1CNR2FNTAFNTB | |
| SCHEMBL3257361 | 0.67 | HTR6 (0.65) | HTR6ALDH1A1 | |
| SCHEMBL4431649 | 0.67 | HTR6 (0.52) | HTR6CYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |