Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921037 | 0.90 | HTR6 (0.41) | HTR6ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL7130815 | 0.87 | ELANE (0.47) | HTR6ELANETSPOALDH1A1DYRK1A | |
| SCHEMBL6921379 | 0.83 | HTR6 (0.38) | HTR6LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL7063772 | 0.78 | HTR7 (0.45) | HTR6LMNAIDO1ALDH1A1DYRK1A | |
| SCHEMBL7124751 | 0.75 | HTR6 (0.41) | HTR6LMNAIDO1ALDH1A1 | |
| SCHEMBL6918823 | 0.74 | AKR1C3 (0.43) | HTR6ELANEALDH1A1KMT2APOLB | |
| SCHEMBL5767433 | 0.72 | HTR6 (0.58) | HTR6 | |
| SCHEMBL6821035 | 0.67 | HTR6 (0.52) | HTR6KMT2AMEN1 | |
| SCHEMBL6922481 | 0.66 | HTR7 (0.49) | HTR6ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL7130820 | 0.66 | DYRK1A (0.49) | HTR6ELANETSPOALDH1A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |