Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919899 | 0.87 | HTR6 (0.43) | ELANEDYRK1AKMT2AALDH1A1HTR6 | |
| SCHEMBL6918823 | 0.87 | AKR1C3 (0.43) | ELANEKDM4EKMT2AALDH1A1THRB | |
| SCHEMBL7130820 | 0.78 | DYRK1A (0.49) | ELANEDYRK1AKDM4EKMT2AALDH1A1 | |
| SCHEMBL6820240 | 0.77 | HTR6 (0.52) | ELANEDYRK1AKDM4EKMT2AALDH1A1 | |
| SCHEMBL6921037 | 0.77 | HTR6 (0.41) | KDM4EKMT2AALDH1A1HTR6HPGD | |
| SCHEMBL6922115 | 0.75 | ELANE (0.44) | ELANENPSR1TSHRTSPO | |
| SCHEMBL7124751 | 0.72 | HTR6 (0.41) | ALDH1A1HTR6TSHR | |
| SCHEMBL6972524 | 0.70 | HTR6 (0.77) | ELANEDYRK1AHTR6HTR1AHTR1D | |
| SCHEMBL6921379 | 0.70 | HTR6 (0.38) | KMT2AALDH1A1HTR6NPSR1TSHR | |
| SCHEMBL6968868 | 0.67 | HTR6 (0.50) | ELANEDYRK1AKMT2AALDH1A1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |