Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124751 | 0.89 | HTR6 (0.41) | HTR6CYP19A1TP53LMNACNR2 | |
| SCHEMBL6919392 | 0.85 | CHRNB2 (0.42) | HTR6LMNASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL6817351 | 0.77 | UTS2R (0.50) | HTR6GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL6921965 | 0.76 | KCNA3 (0.47) | CNR2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL6921037 | 0.76 | HTR6 (0.41) | HTR6MAPTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL3257594 | 0.72 | HTR6 (0.60) | HTR6 | |
| SCHEMBL20769731 | 0.70 | ALDH1A1 (0.58) | HTR6LMNASMN1; SMN2FNTAFNTB | |
| SCHEMBL6918823 | 0.70 | AKR1C3 (0.43) | HTR6ALDH1A1 | |
| SCHEMBL6921379 | 0.69 | HTR6 (0.38) | HTR6MAPTTP53LMNASMN1; SMN2 | |
| SCHEMBL6817354 | 0.66 | HTR7 (0.48) | HTR6CYP19A1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |