Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129202 | 0.87 | NPC1 (0.53) | APPSIGMAR1TMEM97ACKR3DRD2 | |
| SCHEMBL7126384 | 0.81 | SIGMAR1 (0.47) | APPSIGMAR1TMEM97ALDH1A1ACKR3 | |
| SCHEMBL8063854 | 0.81 | KDM4E (0.51) | APPSIGMAR1TMEM97ALDH1A1MEN1 | |
| SCHEMBL7573340 | 0.80 | POLB (0.50) | SIGMAR1TMEM97ALDH1A1MEN1KMT2A | |
| SCHEMBL7129442 | 0.77 | SIGMAR1 (0.60) | APPSIGMAR1TMEM97ACKR3DRD2 | |
| SCHEMBL7169601 | 0.77 | SIGMAR1 (0.57) | APPSIGMAR1TMEM97ACKR3DRD2 | |
| SCHEMBL13579952 | 0.72 | SIGMAR1 (0.83) | APPSIGMAR1TMEM97ACKR3 | |
| SCHEMBL4753614 | 0.71 | ALDH1A1 (0.54) | ALDH1A1HCRTR1MEN1KMT2ADRD2 | |
| SCHEMBL30576437 | 0.70 | APP (0.59) | APPSIGMAR1TMEM97ACKR3 | |
| SCHEMBL10621481 | 0.70 | TMEM97 (0.59) | SIGMAR1TMEM97ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670400-B1 | Secretion inhibitors for gastric acid, antiemetics; N(4-(2-(2-methoxyphenoxy)ethyl)aminobutyl)benzamide; | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2003-12-30 | — | — | US | disclosed |
| EP-0820434-B1 | PHENOXYETHYLAMINE DERIVATIVES HAVING HIGH AFFINITY FOR THE 5-HT 1A RECEPTOR, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SOD CONSEILS RECH APPLIC (FR) | 2000-08-09 | — | — | EP | disclosed |