Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4B | O94953 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.44 |
| ▸ | GLRB | P48167 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129202 | 0.82 | NPC1 (0.53) | MCHR1RAB9ATMEM97SIGMAR1NPC1 | |
| SCHEMBL7564124 | 0.82 | POLB (0.60) | POLBKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL7125002 | 0.80 | APP (0.49) | MEN1KMT2AALDH1A1TMEM97SIGMAR1 | |
| SCHEMBL8063854 | 0.79 | KDM4E (0.51) | POLBKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7126384 | 0.79 | SIGMAR1 (0.47) | HDAC6ALDH1A1RAB9ATMEM97SIGMAR1 | |
| SCHEMBL8022082 | 0.77 | EPHX1 (0.48) | MEN1KMT2AHDAC6MAPTALDH1A1 | |
| SCHEMBL7573338 | 0.76 | HDAC6 (0.47) | POLBKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL7169601 | 0.74 | SIGMAR1 (0.57) | HDAC6RAB9ATMEM97SIGMAR1NPC1 | |
| SCHEMBL7129442 | 0.74 | SIGMAR1 (0.60) | HDAC6RAB9ATMEM97SIGMAR1NPC1 | |
| SCHEMBL10243087 | 0.71 | POLB (0.67) | POLBKDM4EMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929525-B1 | HETEROARYLOXYETHYLAMINES AS 5-HT1A RECEPTOR LIGANDS | SOD CONSEILS RECH APPLIC (FR) | 2002-09-04 | — | — | EP | disclosed |
| US-6063784-A | HYPOTENSIVE AGENTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S. ) (FR) | 2000-05-16 | — | — | US | disclosed |