SCHEMBL7125015

SCHEMBL7125015

O=C(O)CCN1c2ccc(Br)cc2Sc2cc(Br)ccc21

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
LMNA P02545 1/20 0.62
DRD2 P14416 1/20 0.46
HTR2A P28223 1/20 0.46
HTR7 P34969 1/20 0.46
HTR6 P50406 1/20 0.46
MAPT P10636 3/20 0.43
KMO O15229 2/20 0.43
ALDH1A1 P00352 1/20 0.43
FNTA P49354 4/20 0.42
FNTB P49356 4/20 0.42
NOX1 Q9Y5S8 1/20 0.41
KCNK2 O95069 2/20 0.40
KDM4E B2RXH2 1/20 0.38
TP53 P04637 1/20 0.38
MAPK1 P28482 1/20 0.38
CNKSR1 Q969H4 1/20 0.38
APEX1 P27695 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17484559 0.81 MEN1 (0.62) MEN1KMT2ALMNAMAPTKMO
SCHEMBL16156849 0.81 MEN1 (0.62) MEN1KMT2ALMNAMAPTKMO
SCHEMBL16156851 0.80 DRD2 (0.45) MEN1KMT2ALMNADRD2HTR2A
SCHEMBL29947109 0.78 DRD2 (0.51) MEN1KMT2ALMNADRD2HTR2A
SCHEMBL27236434 0.78 DRD2 (0.51) MEN1KMT2ALMNADRD2HTR2A
SCHEMBL7643900 0.78 KMO (0.43) MEN1KMT2ALMNAMAPTKMO
SCHEMBL27236435 0.77 DRD2 (0.48) MEN1KMT2ALMNADRD2HTR2A
SCHEMBL29947281 0.77 DRD2 (0.48) MEN1KMT2ALMNADRD2HTR2A
SCHEMBL31014072 0.77 MEN1 (1.00) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL12073897 0.77 DRD2 (0.53) MEN1KMT2ALMNADRD2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020119136-A1 Antimicrobial peroxidase compositions NOVOZYMES A/S (DK) 2002-08-29 US claimed
JP-2000512267-A 2000-09-19 JP claimed
EP-0912097-A1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVO NORDISK A/S (DK) 1999-05-06 EP claimed
WO-1997042825-A1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVO NORDISK A/S (DK) 1997-11-20 WO claimed
US-6660503-B2 In aqueous solution NOVOZYMES A/S (DK) 2003-12-09 US disclosed
EP-0935692-B1 FABRIC TREATED WITH CELLULASE AND OXIDOREDUCTASE NOVOZYMES AS (DK) 2002-11-27 EP disclosed
US-20020119136-A1 Antimicrobial peroxidase compositions NOVOZYMES A/S (DK) 2002-08-29 US disclosed
EP-0912097-B1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVOZYMES AS (DK) 2002-08-07 EP disclosed
EP-0787230-B1 BLEACHING PROCESS COMPRISING USE OF A PHENOL OXIDIZING ENZYME, A HYDROGEN PEROXIDE SOURCE AND AN ENHANCING AGENT NOVOZYMES AS (DK) 2002-03-20 EP disclosed
US-6346401-B1 OXIDATION OF HYDROXY GROUP OF SUGAR MONOMER OF STARCH BY CONTACTING WITH PEROXIDASE, HYDROGEN PEROXIDE AND ENHANCING AGENT IN AQUEOUS MEDIUM; FORMS CARBONYL OR CARBOXYLATE GROUP NOVOZYMES A/S (DK) 2002-02-12 US disclosed
US-20010055794-A1 Modification of polysaccharides by means of a phenol oxidizing enzyme NOVOZYMES A/S (DK) 2001-12-27 US disclosed
EP-0946207-B1 A METHOD FOR ENZYMATIC TREATMENT OF BIOFILM NOVOZYMES AS (DK) 2001-10-24 EP disclosed
US-5851233-A Bleaching process comprising use of a phenol oxidizing enzyme, a hydrogen peroxide source and an enhancing agent NOVO NORDISK A/S (DK) 1998-12-22 US disclosed
WO-1998026807-A1 A METHOD FOR ENZYMATIC TREATMENT OF BIOFILM NOVO NORDISK A/S (DK) 1998-06-25 WO disclosed
WO-1997042825-A1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVO NORDISK A/S (DK) 1997-11-20 WO disclosed
WO-1997040229-A1 FABRIC TREATED WITH A CELLULASE AND A HYBRID ENZYME COMPRISING A PHENOL OXIDIZING ENZYME NOVO NORDISK A/S (DK) 1997-10-30 WO disclosed
WO-1997040127-A1 BLEACHING OF FABRIC WITH A HYBRID ENZYME CONTAINING A PHENOL OXIDIZING ENZYME FUSED TO A CELLULOSE BINDING DOMAIN NOVO NORDISK A/S (DK) 1997-10-30 WO disclosed
EP-0787230-A1 BLEACHING PROCESS COMPRISING USE OF A PHENOL OXIDIZING ENZYME, A HYDROGEN PEROXIDE SOURCE AND AN ENHANCING AGENT NOVO NORDISK A/S (DK) 1997-08-06 EP disclosed
WO-1997025468-A1 FABRIC TREATED WITH CELLULASE AND OXIDOREDUCTASE NOVO NORDISK A/S (DK) 1997-07-17 WO disclosed
WO-1996012846-A1 BLEACHING PROCESS COMPRISING USE OF A PHENOL OXIDIZING ENZYME, A HYDROGEN PEROXIDE SOURCE AND AN ENHANCING AGENT NOVO NORDISK A/S (DK) 1996-05-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020119136-A1 Antimicrobial peroxidase compositions LPO, MPO, GPX4 MEN1 4044/4885KMT2A 4375/4885LMNA 3666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.