Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7117163 | 0.98 | MAOA (0.50) | MAOAMAOBKDM1APDPK1SLC18A3 | |
| SCHEMBL2322457 | 0.82 | PDPK1 (0.70) | MAOAMAOBKDM1APDPK1SLC18A3 | |
| Hydrochloric Acid SCHEMBL7123292 | 0.80 | PDPK1 (0.68) | MAOAMAOBKDM1APDPK1SLC18A3 | |
| SCHEMBL7127619 | 0.80 | P2RX7 (0.40) | MAOAMAOBCA1CA2BCHE | |
| Hydrochloric Acid SCHEMBL7120126 | 0.78 | P2RX7 (0.39) | CA1CA2BCHEACHEALDH1A1 | |
| SCHEMBL6863573 | 0.76 | BCHE (0.53) | BCHEACHEALDH1A1TP53CYP3A4 | |
| SCHEMBL15131188 | 0.75 | PDPK1 (0.61) | MAOAMAOBKDM1APDPK1SLC18A3 | |
| SCHEMBL3702992 | 0.75 | BCHE (0.56) | BCHEACHESMN1; SMN2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6863833 | 0.75 | BCHE (0.51) | BCHEACHEALDH1A1TP53CYP3A4 | |
| SCHEMBL18988275 | 0.72 | S100A4 (0.44) | MAOBKDM4EMEN1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874800-B1 | INDANE DIMER COMPOUNDS WITH SMOOTH MUSCLE RELAXING AND/OR MAST CELL STABILISING AND/OR ANTIINFLAMMATORY ACTIVITY | VENANTIUS LTD (IE) | 2003-08-06 | — | — | EP | claimed |
| US-6423752-B1 | SUCH AS 3-(N-1-INDANYLAMINO)-INDAN-1-ONE 3-(N-1-INDANYLAMINO) INDAN-1-ONE FORMED BY REACTING AMINO-INDANE COMPOUND WITH BROMO-INDANONE COMPOUND IN PRESENCE OF TRIETHYLENEAMINE | VENANTIUS LIMITED (IE) | 2002-07-23 | — | — | US | claimed |
| US-20020052530-A1 | INDANE DIMER COMPOUNDS WITH SMOOTH MUSCLE RELAXING AND/OR MAST CELL STABILISING AND/OR ANTIINFLAMMATORY ACTIVITY | VENANTIUS LIMITED (IE) | 2002-05-02 | — | — | US | claimed |
| EP-0874800-B1 | INDANE DIMER COMPOUNDS WITH SMOOTH MUSCLE RELAXING AND/OR MAST CELL STABILISING AND/OR ANTIINFLAMMATORY ACTIVITY | VENANTIUS LTD (IE) | 2003-08-06 | — | — | EP | disclosed |
| US-6423752-B1 | SUCH AS 3-(N-1-INDANYLAMINO)-INDAN-1-ONE 3-(N-1-INDANYLAMINO) INDAN-1-ONE FORMED BY REACTING AMINO-INDANE COMPOUND WITH BROMO-INDANONE COMPOUND IN PRESENCE OF TRIETHYLENEAMINE | VENANTIUS LIMITED (IE) | 2002-07-23 | — | — | US | disclosed |
| WO-1997020805-A1 | INDANE DIMER COMPOUNDS WITH SMOOTH MUSCLE RELAXING AND/OR MAST CELL STABILISING AND/OR ANTIINFLAMMATORY ACTIVITY | VENANTIUS LIMITED (IE) | 1997-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052530-A1 | INDANE DIMER COMPOUNDS WITH SMOOTH MUSCLE RELAXING AND/OR MAST CELL STABILISING AND/OR ANTIINFLAMMATORY ACTIVITY | MYLK, HRH2, HRH1 | MAOA 914/4885MAOB 1176/4885KDM1A 2119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.