Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.51 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1526618 | 0.83 | ACMSD (0.51) | DHODHACMSDGPR35HNF4ACYP2E1 | |
| SCHEMBL7130701 | 0.82 | SLC6A3 (0.49) | DHODHTMIGD3ADORA2AHSD17B10KDM4E | |
| SCHEMBL7119865 | 0.81 | G6PD (0.47) | DHODHACMSDGPR35HNF4ACYP2E1 | |
| SCHEMBL121804 | 0.79 | HNF4A (0.63) | DHODHACMSDHNF4AHSD17B10ALB | |
| SCHEMBL19923221 | 0.78 | HSD17B10 (0.59) | DHODHACMSDHNF4AHSD17B10ALB | |
| SCHEMBL16875857 | 0.77 | GPR35 (0.41) | DHODHACMSDGPR35TMIGD3ADORA2A | |
| SCHEMBL9358502 | 0.76 | SLC6A4 (0.51) | DHODHACMSDGPR35HNF4AHSD17B10 | |
| SCHEMBL21944859 | 0.76 | TMIGD3 (0.48) | ACMSDTMIGD3ADORA2AADORA1CYP2E1 | |
| SCHEMBL15025193 | 0.75 | ACMSD (0.59) | ACMSDGPR35TMIGD3ADORA2AADORA1 | |
| SCHEMBL6438260 | 0.75 | PDGFRB (0.45) | TMIGD3ADORA2AADORA1CYP2E1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
| WO-2001087845-A2 | N-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS 5-HT ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, GNE, NIT2 | DHODH 2195/4885ACMSD 87/4885GPR35 633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.