Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.86 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.86 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | USP8 | P40818 | 1/20 | 0.64 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.52 |
| ▸ | GPR27 | Q9NS67 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | PLAT | P00750 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128814 | 0.93 | SLC20A2 (1.00) | SLC20A2SLC20A1USP2USP8AVPR2 | |
| SCHEMBL7208743 | 0.89 | SLC20A2 (0.70) | SLC20A2SLC20A1USP2USP8AVPR2 | |
| SCHEMBL7120286 | 0.85 | SLC20A2 (0.74) | SLC20A2SLC20A1AVPR2GPR27MEN1 | |
| SCHEMBL7126685 | 0.83 | SLC20A2 (0.83) | SLC20A2SLC20A1USP2USP8AVPR2 | |
| SCHEMBL27575234 | 0.81 | SLC20A2 (0.57) | SLC20A2SLC20A1USP8AVPR2GPR27 | |
| SCHEMBL7530790 | 0.79 | SLC20A2 (0.65) | SLC20A2SLC20A1AVPR2GPR27MEN1 | |
| SCHEMBL7144951 | 0.79 | GPR27 (0.70) | SLC20A2SLC20A1USP2USP8AVPR2 | |
| SCHEMBL7572438 | 0.78 | SLC20A2 (0.63) | SLC20A2SLC20A1USP2USP8MEN1 | |
| SCHEMBL12201483 | 0.78 | SLC20A2 (0.72) | SLC20A2SLC20A1USP2USP8MEN1 | |
| SCHEMBL23200355 | 0.77 | MEN1 (0.67) | SLC20A2SLC20A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458845-B1 | METHOD OF ANTAGONIZING A MACROPHAGE SCAVENGER RECEPTOR COMPRISING ADMINISTERING TO A SUBJECT IN NEED OF TREATMENT AN EFFECTIVE AMOUNT OF AN N-PHENYL-2-(3-TRIFLUOROMETHYLPHENYLSULFONAMIDO)BENZAMIDE, A | SMITHKLINE BEECHAM CORPORATION | 2002-10-01 | — | — | US | claimed |