SCHEMBL7127211

SCHEMBL7127211

NP(=O)(O)OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H]1O

nearest known ligand 0.80

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 8/20 0.80
P2RY2 P41231 12/20 0.78
P2RY4 P51582 6/20 0.78
P2RY14 Q15391 7/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL285071 0.91 P2RY6 (0.83) P2RY6P2RY2P2RY4P2RY14
SCHEMBL157645 0.91 P2RY6 (0.83) P2RY6P2RY2P2RY4P2RY14
SCHEMBL2056916 0.91 P2RY6 (0.83) P2RY6P2RY2P2RY4P2RY14
SCHEMBL2683846 0.91 P2RY6 (0.83) P2RY6P2RY2P2RY4P2RY14
SCHEMBL4071893 0.91 P2RY6 (0.83) P2RY6P2RY2P2RY4P2RY14
SCHEMBL4166158 0.91 P2RY6 (0.83) P2RY6P2RY2P2RY4P2RY14
SCHEMBL2056922 0.91 P2RY6 (0.83) P2RY6P2RY2P2RY4P2RY14
SCHEMBL2056709 0.91 P2RY6 (0.83) P2RY6P2RY2P2RY4P2RY14
SCHEMBL157644 0.91 P2RY6 (0.83) P2RY6P2RY2P2RY4P2RY14
SCHEMBL30679287 0.91 P2RY6 (0.83) P2RY6P2RY2P2RY4P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091050-A1 ADVANTAGEOUS ANTI-HCV COMBINATION THERAPY Atea Pharmaceuticals, Inc. (US) 2026-04-02 US disclosed
EP-4667053-A2 BETA-D-2'-DEOXY-2'ALPHA-FLUORO-2'-BETA-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT ATEA Pharmaceuticals, Inc. (US) 2025-12-24 EP disclosed
US-12458656-B2 Advantageous anti-HCV combination therapy Atea Pharmaceuticals, Inc. (US) 2025-11-04 US disclosed
US-20250281520-A1 ADVANTAGEOUS ANTI-HCV COMBINATION THERAPY Atea Pharmaceuticals, Inc. (US) 2025-09-11 US disclosed
EP-3265102-B1 BETA-D-2'-DEOXY-2'ALPHA-FLUORO-2'-BETA-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT ATEA PHARMACEUTICALS INC (US) 2025-08-20 EP disclosed
US-20250243235-A1 Beta-D-2'-DEOXY-2'-alpha-FLUORO-2'-Beta-C-SUBSTITUTED-2-MODIFIED-N6- SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT Atea Pharmaceuticals, Inc. (US) 2025-07-31 US disclosed
US-20250109163-A1 NUCLEOTIDE HEMI-SULFATE SALT FOR THE TREATMENT OF HEPATITIS C VIRUS Atea Pharmaceuticals, Inc. (US) 2025-04-03 US disclosed
EP-3577124-B1 NUCLEOTIDE HEMI-SULFATE SALT FOR THE TREATMENT OF HEPATITIS C VIRUS ATEA PHARMACEUTICALS INC (US) 2024-12-11 EP disclosed
EP-4450129-A2 NUCLEOTIDE HEMI-SULFATE SALT FOR THE TREATMENT OF HEPATITIS C VIRUS ATEA Pharmaceuticals, Inc. (US) 2024-10-23 EP disclosed
US-12084473-B2 β-D-2′-deoxy-2′-α-fluoro-2′-β-C-substituted-2-modified-N6-substituted purine nucleotides for HCV treatment Atea Pharmaceuticals, Inc. (US) 2024-09-10 US disclosed
WO-2018013937-A1 BETA-D-2'-DEOXY-2'-ALPHA-FLUORO-2'-BETA-C-SUBSTITUTED-4'-FLUORO-N6-SUBSTITUTED-6-AMINO-2-SUBSTITUTED PURINE NUCLEOTIDES FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTION Atea Pharmaceuticals, Inc. (US) 2018-01-18 WO disclosed
EP-3265102-A1 BETA-D-2'-DEOXY-2'ALPHA-FLUORO-2'-BETA-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT ATEA Pharmaceuticals, Inc. (US) 2018-01-10 EP disclosed
CN-107427530-A β -D-2 ' -deoxy-2 ' α -fluoro-2 ' - β -C-substituted-2-modified-N for HCV treatment6-substituted purine nucleotides 阿堤亚制药公司 2017-12-01 CN disclosed
US-9828410-B2 β-D-2′-deoxy-2′-α-fluoro-2′-β-C-substituted-2-modified-N6-substituted purine nucleotides for HCV treatment Atea Pharmaceuticals, Inc. (US) 2017-11-28 US disclosed
CN-107074899-A Improved flaorination process 桑多斯股份公司 2017-08-18 CN disclosed
WO-2016144918-A1 β-D-2'-DEOXY-2'α-FLUORO-2'-β-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT Atea Pharmaceuticals, Inc. (US) 2016-09-15 WO disclosed
US-20160257706-A1 Beta-D-2'-DEOXY-2'-alpha-FLUORO-2'-beta-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT Atea Pharmaceuticals, Inc. (US) 2016-09-08 US disclosed
WO-2016014527-A2 STABILIZED NUCLEOTIDES FOR MEDICAL TREATMENT ACHILLION PHARMACEUTICALS, INC. (US) 2016-01-28 WO disclosed
US-20160016986-A1 STABILIZED NUCLEOTIDES FOR MEDICAL TREATMENT ACHILLION PHARMACEUTICALS, INC. 2016-01-21 US disclosed
JP-2003252894-A METHOD OF PRODUCTION FOR URIDINE-5'-DIPHOSPHATE OLIGOSACCHARIDE NOGUCHI INST 2003-09-10 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160016986-A1 STABILIZED NUCLEOTIDES FOR MEDICAL TREATMENT NUDT1, DUT, ADAR P2RY6 271/4885P2RY2 315/4885P2RY4 249/4885
US-20250109163-A1 NUCLEOTIDE HEMI-SULFATE SALT FOR THE TREATMENT OF HEPATITIS C VIRUS HAVCR2, HCCS, SLC10A1 P2RY6 2493/4885P2RY2 3315/4885P2RY4 2658/4885
US-12084473-B2 β-D-2′-deoxy-2′-α-fluoro-2′-β-C-substituted-2-modified-N6-substituted purine nucleotides for HCV treatment NSUN2, PNP, NUDT1 P2RY6 71/4885P2RY2 50/4885P2RY4 72/4885
US-12458656-B2 Advantageous anti-HCV combination therapy HAVCR2, SLC10A1, EIF2AK2 P2RY6 3717/4885P2RY2 3823/4885P2RY4 4047/4885
US-20250243235-A1 Beta-D-2'-DEOXY-2'-alpha-FLUORO-2'-Beta-C-SUBSTITUTED-2-MODIFIED-N6- SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT NSUN2, NUDT1, DCTD P2RY6 149/4885P2RY2 84/4885P2RY4 136/4885
US-20250281520-A1 ADVANTAGEOUS ANTI-HCV COMBINATION THERAPY HAVCR2, SLC10A1, EIF2AK2 P2RY6 3717/4885P2RY2 3823/4885P2RY4 4047/4885
US-20260091050-A1 ADVANTAGEOUS ANTI-HCV COMBINATION THERAPY SLC10A1, SLC10A2, STAT3 P2RY6 2210/4885P2RY2 1201/4885P2RY4 1861/4885
US-20160257706-A1 Beta-D-2'-DEOXY-2'-alpha-FLUORO-2'-beta-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT NSUN2, NUDT1, DCTD P2RY6 149/4885P2RY2 84/4885P2RY4 136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.