Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 4/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 8/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011689 | 0.84 | KMT2A (0.44) | FNTAFNTB | |
| SCHEMBL7127730 | 0.84 | ADRB1 (0.35) | ADRB1FNTAFNTBNR1H3NR1H2 | |
| SCHEMBL6011781 | 0.78 | GPR119 (0.44) | NR1H3NR1H2 | |
| SCHEMBL6647263 | 0.76 | HTR2C (0.36) | NR1H3NR1H2 | |
| SCHEMBL5075648 | 0.76 | HTR6 (0.46) | ADRB1 | |
| SCHEMBL5077591 | 0.74 | ALDH1A1 (0.41) | — | |
| SCHEMBL6011570 | 0.74 | TP53 (0.42) | — | |
| SCHEMBL6011375 | 0.73 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL5078902 | 0.73 | KMT2A (0.49) | — | |
| SCHEMBL6648472 | 0.73 | HTR2C (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112251-B1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-05-07 | — | — | EP | claimed |