Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7169198 | 0.84 | ALDH1A1 (0.51) | MRGPRX4S1PR5HPGDNPC1RAB9A | |
| SCHEMBL7169194 | 0.84 | ALDH1A1 (0.51) | MRGPRX4S1PR5HPGDNPC1RAB9A | |
| SCHEMBL8512033 | 0.80 | SLC6A2 (0.57) | MRGPRX4S1PR5HPGDNPC1RAB9A | |
| SCHEMBL4747320 | 0.79 | MAOB (0.59) | MRGPRX4S1PR5HPGDNPC1RAB9A | |
| SCHEMBL229472 | 0.78 | MRGPRX4 (0.69) | MRGPRX4S1PR5HPGDRAB9APTGER1 | |
| SCHEMBL7127765 | 0.78 | MAPT (0.52) | MRGPRX4S1PR5HPGDNPC1RAB9A | |
| SCHEMBL7127771 | 0.78 | MAPT (0.52) | MRGPRX4S1PR5HPGDNPC1RAB9A | |
| SCHEMBL8883324 | 0.77 | RXRA (0.43) | MRGPRX4HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7128516 | 0.77 | MAOB (0.51) | MRGPRX4FFAR1PPARD | |
| SCHEMBL31031135 | 0.76 | MRGPRX4 (0.56) | MRGPRX4S1PR5HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6666989-B1 | Electrical and electro-optic apparatus comprising spaced glass panels having polyethers and electrodes on the interior surfaces, used as detectors, screens and in nonlinear optical apparatus | QINETIQ LIMITED (GB) | 2003-12-23 | — | — | US | disclosed |