SCHEMBL7574531

SCHEMBL7574531

CCC(C)(O)c1ccccc1C(C)(O)CC

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
ALDH1A1 P00352 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
CA2 P00918 1/20 0.39
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
PKM P14618 1/20 0.38
KMT2A Q03164 1/20 0.38
RIPK1 Q13546 3/20 0.37
GABRA1 P14867 2/20 0.33
GABRB2 P47870 2/20 0.33
CYP2C19 P33261 3/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
HIF1A Q16665 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10599295 0.93 ALDH1A1 (0.38) TSHRALDH1A1TDP1HSP90AA1HSP90AB1
SCHEMBL7550163 0.86 ALDH1A1 (0.58) TSHRALDH1A1TDP1HSP90AA1HSP90AB1
SCHEMBL19130505 0.86 GABRA1 (0.42) TSHRALDH1A1TDP1HSP90AA1HSP90AB1
SCHEMBL7127844 0.86 GABRA1 (0.42) TSHRALDH1A1TDP1HSP90AA1HSP90AB1
SCHEMBL24538831 0.84 RIPK1 (0.40) TSHRALDH1A1TDP1HSP90AA1HSP90AB1
SCHEMBL18759138 0.84 ALDH1A1 (0.36) TSHRALDH1A1TDP1HSP90AA1HSP90AB1
SCHEMBL16387926 0.81 PDCD1 (0.39) TSHRALDH1A1HSP90AA1HSP90AB1MEN1
SCHEMBL2482276 0.81 ALDH1A1 (0.39) TSHRALDH1A1TDP1CYP2C19CYP2D6
SCHEMBL7544546 0.78 HSP90AA1 (0.33) TSHRALDH1A1TDP1HSP90AA1HSP90AB1
SCHEMBL2515113 0.78 HSP90AA1 (0.36) TSHRALDH1A1TDP1HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4968759-A Phenolic polymer and production thereof HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-11-06 US claimed
EP-0945420-B1 Process for the preparation of bisphenols MITSUI CHEMICALS INC (JP) 2002-06-12 EP disclosed
US-6316677-B1 REACTING PHENOLIC COMPOUND WITH DIALKYLBENZENE, BIS(HYDROXYALKYL)BENZENE, OR (HYDROXYALKYL)-ALKENYLBENZENE; NEUTRALIZATION USING ANION EXCHANGE RESIN; CONCENTRATION, ISOLATION MITSUI CHEMICALS, INC. (JP) 2001-11-13 US disclosed
EP-0945420-A1 Process for the preparation of bisphenols Mitsui Chemicals, Inc. (JP) 1999-09-29 EP disclosed
US-5102962-A Phenolic polymer and production thereof HITACHI CHEMICAL COMPANY, LTD. (JP) 1992-04-07 US disclosed
US-4968759-A Phenolic polymer and production thereof HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-11-06 US disclosed
US-4897438-A BLEND WITH A PHENOLIC RESIN HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-01-30 US disclosed