Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2277923 | 0.87 | CHRNB2 (0.53) | CHRNB2CHRNA4 | |
| SCHEMBL2269363 | 0.84 | HTR2C (0.47) | — | |
| SCHEMBL2272330 | 0.84 | HTR3A (0.56) | — | |
| SCHEMBL14320596 | 0.84 | GABRA1 (0.44) | — | |
| SCHEMBL22555632 | 0.80 | USP30 (0.51) | CHRNB2CHRNA4 | |
| SCHEMBL27472190 | 0.78 | PTGS2 (0.58) | — | |
| SCHEMBL2278345 | 0.78 | HTR7 (0.48) | — | |
| SCHEMBL5839494 | 0.76 | HTR2C (0.47) | — | |
| SCHEMBL3121349 | 0.76 | HTR2C (0.56) | — | |
| SCHEMBL27597855 | 0.76 | HTR2C (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030134859-A1 | PPAR-gamma modulator | SANKYO COMPANY, LIMITED (JP) | 2003-07-17 | — | — | US | disclosed |
| EP-1277729-A1 | PPAR (GAMMA) MODULATORS | Sankyo Company, Limited (JP) | 2003-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134859-A1 | PPAR-gamma modulator | PPARG, PPARA, PPARD | CHRNB2 1470/4885CHRNA4 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.