Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.40 |
| ▸ | CFTR | P13569 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6917789 | 0.88 | MEN1 (0.35) | PLA2G2AMAPK8AKR1B10AKR1A1AKR1B1 | |
| SCHEMBL6920637 | 0.86 | PLA2G2A (0.49) | PLA2G2ANPC1TSHRALDH1A1MAPT | |
| SCHEMBL6918965 | 0.86 | CYP19A1 (0.46) | NPC1TSHRALDH1A1MAPTPOLB | |
| SCHEMBL7129939 | 0.78 | TSPO (0.40) | PLA2G2AMAPK8CFTRNPC1AKR1B10 | |
| SCHEMBL6922115 | 0.78 | ELANE (0.44) | PLA2G2AMAPK8TSHRTSPOLMNA | |
| SCHEMBL3855156 | 0.77 | GRIK2 (0.50) | PLA2G2AMAPK8CFTRNPC1TSHR | |
| SCHEMBL6920117 | 0.74 | CA12 (0.48) | PLA2G2AMAPK8CFTRNPC1AKR1B10 | |
| SCHEMBL6922120 | 0.74 | MAPT (0.42) | PLA2G2ATSHRALDH1A1MAPTPOLB | |
| SCHEMBL3853087 | 0.73 | PLA2G2A (0.49) | PLA2G2AMAPK8CFTRNPC1AKR1B10 | |
| SCHEMBL3852451 | 0.73 | PLA2G2A (0.49) | PLA2G2AMAPK8CFTRNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |