Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128402 | 0.88 | PTGS2 (0.47) | AGTR1PTGS2ABCB1LMNACYP1A2 | |
| SCHEMBL6919741 | 0.87 | AGTR1 (0.55) | ELANEAGTR1PTGS2ABCB1LMNA | |
| SCHEMBL6922117 | 0.80 | ELANE (0.43) | ELANEAGTR1PTGS2ABCB1LMNA | |
| SCHEMBL6820229 | 0.78 | ALDH1A1 (0.43) | ELANEAGTR1PTGS2ABCB1LMNA | |
| SCHEMBL6920262 | 0.78 | AGTR1 (0.39) | AGTR1PTGS2ABCB1CYP1A2CYP2C9 | |
| SCHEMBL7129936 | 0.78 | PLA2G2A (0.41) | LMNATSHRNPSR1PLA2G2AMAPK8 | |
| SCHEMBL6471641 | 0.75 | POLB (0.45) | AGTR1LMNATSHRNPSR1P2RX4 | |
| SCHEMBL7130815 | 0.75 | ELANE (0.47) | ELANETSHRNPSR1TSPO | |
| SCHEMBL6917789 | 0.75 | MEN1 (0.35) | ABCB1TSHRNPSR1PLA2G2AMAPK8 | |
| SCHEMBL6920229 | 0.73 | P2RX4 (0.47) | ELANEAGTR1PTGS2ABCB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |