Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920639 | 0.87 | PLA2G2A (0.47) | TSPOPLA2G2ANPC1KMT2ALMNA | |
| SCHEMBL6918967 | 0.87 | CYP19A1 (0.44) | NPC1KMT2AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL6922117 | 0.78 | ELANE (0.43) | TSPOPLA2G2ALMNAHIF1ATSHR | |
| SCHEMBL7129936 | 0.78 | PLA2G2A (0.41) | TSPOPLA2G2AMAPK8CFTRNPC1 | |
| SCHEMBL3855156 | 0.75 | GRIK2 (0.50) | PLA2G2AMAPK8CFTRNPC1KMT2A | |
| SCHEMBL6922123 | 0.75 | MAPT (0.41) | PLA2G2AKMT2ALMNATSHRMAPK1 | |
| SCHEMBL6822016 | 0.73 | UTS2R (0.39) | MAPK8KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL6920117 | 0.73 | CA12 (0.48) | TSPOPLA2G2AMAPK8CFTRNPC1 | |
| SCHEMBL3853087 | 0.72 | PLA2G2A (0.49) | PLA2G2AMAPK8CFTRNPC1KMT2A | |
| SCHEMBL6917019 | 0.72 | ESR1 (0.48) | KMT2AMEN1ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |