SCHEMBL7130240

SCHEMBL7130240

O=C1OCCC1C(O)CC1CC2C=CC1C2

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.35
TDO2 P48775 1/20 0.35
KDM4E B2RXH2 8/20 0.33
ALDH1A1 P00352 4/20 0.33
TDP1 Q9NUW8 3/20 0.33
TSHR P16473 1/20 0.32
PKM P14618 2/20 0.31
MEN1 O00255 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7126364 0.79 KDM4E (0.32) IDO1TDO2KDM4EALDH1A1TDP1
SCHEMBL7119984 0.76 KDM4E (0.32) KDM4E
SCHEMBL9908399 0.72 MEN1 (0.32) ALDH1A1MEN1KMT2A
SCHEMBL10976261 0.70 KDM4E (0.38) IDO1TDO2KDM4EALDH1A1TDP1
SCHEMBL14330304 0.69
SCHEMBL6276072 0.69 LMNA (0.39)
SCHEMBL4833162 0.69 LMNA (0.39)
SCHEMBL13986503 0.69 LMNA (0.39)
SCHEMBL14117842 0.69 KDM4E (0.43) IDO1TDO2KDM4EALDH1A1TDP1
SCHEMBL10946796 0.69 KDM4E (0.42) IDO1TDO2KDM4EALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6660448-B2 Lactone ring-substituted norbornene based polymers; photoresists; resolution, etching resistance, use in micropatterning with electron beams or deep-ultraviolet radation SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-12-09 US disclosed
US-6500961-B2 MICROSTRUCTURE PATTERNS FOR PHOTORESISTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-12-31 US disclosed
US-20020091215-A1 Polymer, resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-07-11 US disclosed
US-20020019545-A1 Novel lactone compounds having alicyclic structure and their manufacturing method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019545-A1 Novel lactone compounds having alicyclic structure and their manufacturing method RACK1, MRPS22, ECH1 IDO1 4161/4885TDO2 4708/4885KDM4E 788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.