Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | DRD4 | P21917 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129424 | 0.86 | NPC1 (0.65) | DRD2DRD4DRD3NPC1RAB9A | |
| SCHEMBL7565853 | 0.81 | MCHR1 (0.48) | DRD2DRD4DRD3NPC1SMN1; SMN2 | |
| SCHEMBL7570866 | 0.80 | NPC1 (0.49) | DRD2DRD4DRD3NPC1SMN1; SMN2 | |
| SCHEMBL7564124 | 0.80 | POLB (0.60) | NPC1SMN1; SMN2RAB9AHDAC6KDM4E | |
| SCHEMBL7565857 | 0.79 | HTR1A (0.48) | DRD2DRD4DRD3NPC1SMN1; SMN2 | |
| SCHEMBL8779817 | 0.76 | HDAC1 (0.79) | NPC1SMN1; SMN2RAB9AHPGDHDAC1 | |
| SCHEMBL9489804 | 0.74 | HDAC1 (0.82) | NPC1SMN1; SMN2RAB9AHDAC1HDAC2 | |
| SCHEMBL9188890 | 0.74 | HDAC1 (0.82) | NPC1SMN1; SMN2RAB9AHDAC1HDAC2 | |
| SCHEMBL20734829 | 0.74 | HDAC1 (0.82) | NPC1SMN1; SMN2RAB9AHDAC1HDAC2 | |
| SCHEMBL7460068 | 0.74 | HDAC1 (0.82) | NPC1SMN1; SMN2RAB9AHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670400-B1 | Secretion inhibitors for gastric acid, antiemetics; N(4-(2-(2-methoxyphenoxy)ethyl)aminobutyl)benzamide; | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2003-12-30 | — | — | US | claimed |
| EP-0820434-B1 | PHENOXYETHYLAMINE DERIVATIVES HAVING HIGH AFFINITY FOR THE 5-HT 1A RECEPTOR, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SOD CONSEILS RECH APPLIC (FR) | 2000-08-09 | — | — | EP | claimed |
| EP-0820434-A1 | PHENOXYETHYLAMINE DERIVATIVES HAVING HIGH AFFINITY FOR THE 5-HT 1A RECEPTOR, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-01-28 | — | — | EP | claimed |
| WO-1996031461-A1 | PHENOXYETHYLAMINE DERIVATIVES HAVING HIGH AFFINITY FOR THE 5-HT1A RECEPTOR, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1996-10-10 | — | — | WO | claimed |
| US-6670400-B1 | Secretion inhibitors for gastric acid, antiemetics; N(4-(2-(2-methoxyphenoxy)ethyl)aminobutyl)benzamide; | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2003-12-30 | — | — | US | disclosed |
| EP-0820434-B1 | PHENOXYETHYLAMINE DERIVATIVES HAVING HIGH AFFINITY FOR THE 5-HT 1A RECEPTOR, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SOD CONSEILS RECH APPLIC (FR) | 2000-08-09 | — | — | EP | disclosed |
| EP-0820434-A1 | PHENOXYETHYLAMINE DERIVATIVES HAVING HIGH AFFINITY FOR THE 5-HT 1A RECEPTOR, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-01-28 | — | — | EP | disclosed |
| WO-1996031461-A1 | PHENOXYETHYLAMINE DERIVATIVES HAVING HIGH AFFINITY FOR THE 5-HT1A RECEPTOR, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1996-10-10 | — | — | WO | disclosed |