Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | CYBB | P04839 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570866 | 0.86 | NPC1 (0.49) | HTR1ASLC6A4SMN1; SMN2NPC1HPGD | |
| SCHEMBL7564124 | 0.83 | POLB (0.60) | HTR1ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7130472 | 0.79 | DRD2 (0.55) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL7129424 | 0.78 | NPC1 (0.65) | HTR1ANPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL15923242 | 0.73 | HTR1A (0.68) | HTR1A | |
| SCHEMBL31197382 | 0.73 | HTR1A (0.68) | HTR1A | |
| SCHEMBL19463219 | 0.73 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL23412188 | 0.72 | NCF1 (0.51) | HTR1ASLC6A4CYBBNCF1SMN1; SMN2 | |
| SCHEMBL15922854 | 0.72 | HTR1A (0.70) | HTR1A | |
| SCHEMBL31197365 | 0.72 | HTR1A (0.70) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929525-B1 | HETEROARYLOXYETHYLAMINES AS 5-HT1A RECEPTOR LIGANDS | SOD CONSEILS RECH APPLIC (FR) | 2002-09-04 | — | — | EP | claimed |
| EP-0929525-A2 | NOVEL HETEROARYLOXYETHYLAMINES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-07-21 | — | — | EP | claimed |
| WO-1998013349-A2 | HETEROARYLOXYETHYLAMINES AS 5-HT1A LIGANDS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-04-02 | — | — | WO | claimed |
| EP-0929525-B1 | HETEROARYLOXYETHYLAMINES AS 5-HT1A RECEPTOR LIGANDS | SOD CONSEILS RECH APPLIC (FR) | 2002-09-04 | — | — | EP | disclosed |
| US-6063784-A | HYPOTENSIVE AGENTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S. ) (FR) | 2000-05-16 | — | — | US | disclosed |
| EP-0929525-A2 | NOVEL HETEROARYLOXYETHYLAMINES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013349-A2 | HETEROARYLOXYETHYLAMINES AS 5-HT1A LIGANDS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-04-02 | — | — | WO | disclosed |